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HGF Produits

(Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))

Catégories

Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Catégories HGF en vedette

HGF Anticorps

High quality antibodies with extensive validation data.

HGF Kits ELISA

Reliable ELISA kits for a wide range of species.

HGF Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HGF recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, PLA
Validations
  • (1)
  • (5)
N° du produit ABIN516424
Quantité 100 μg
Fiche technique Fiche technique

Application WB, IHC
Validations
  • (5)
  • (8)
N° du produit ABIN2781816
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (2)
  • (3)
N° du produit ABIN388462
Quantité 400 μL
Fiche technique Fiche technique

HGF recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (9)
  • (1)
N° du produit ABIN6956494
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6956495
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (8)
  • (1)
N° du produit ABIN6956496
Quantité 96 tests
Fiche technique Fiche technique

HGF recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7274808
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7274810
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source CHO Cells
Validations
  • (2)
N° du produit ABIN2017955
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits HGF

Harrison, Siller, Tanaka, Chollet, de la Morena-Barrio, Xiang, Patterson, Andersen, Bravo-Pérez, Kempf, Åsrud, Lunov, Dejneka, Mowinckel, Stavik, Sandset, Melum, Baumgarten, Bonanini, Kurek et al.: "Scalable production of tissue-like vascularized liver organoids from human PSCs. ..." dans: Experimental & molecular medicine, Vol. 55, Issue 9, pp. 2005-2024, (2023) (PubMed).

Zhang, Olsavszky, Yin, Wang, Engleitner, Öllinger, Schledzewski, Koch, Rad, Schmid, Friess, Goerdt, Hüser, Géraud, von Figura, Hartmann: "Angiocrine Hepatocyte Growth Factor Signaling Controls Physiological Organ and Body Size and Dynamic Hepatocyte Proliferation to Prevent Liver Damage during Regeneration." dans: The American journal of pathology, Vol. 190, Issue 2, pp. 358-371, (2020) (PubMed).

Ding, You, Tian, Gu, Deng: "Chidamide increases the sensitivity of Non-small Cell Lung Cancer to Crizotinib by decreasing c-MET mRNA methylation." dans: International journal of biological sciences, Vol. 16, Issue 14, pp. 2595-2611, (2020) (PubMed).

Ozturk, Ozturk, Cerrah, Atamanalp, Gul, Aksungur, Bakan, Bakan: "Evaluation of liver function by means of serum cytokeratin 18 and hepatocyte growth factor levels in patients with obstructive jaundice." dans: Acta chirurgica Belgica, Vol. 118, Issue 3, pp. 167-171, (2019) (PubMed).

Brige, Hery, Palen, Guilbaud, Buffat, Moyon, Hardwigsen, Guedj, Guillet, Vidal, Gorincour, Chopinet, Gregoire: "Portal vein stenosis preconditioning of living donor liver in swine: early mechanisms of liver regeneration and gain of hepatic functional mass." dans: American journal of physiology. Gastrointestinal and liver physiology, Vol. 315, Issue 1, pp. G117-G125, (2019) (PubMed).

Ariyati, Handono, Nurdiana, Wirohadidjojo: "What is the Best Degree of Hyaluronic Acid Crosslinking in Increasing Growth Factors Level of Platelet-Rich Fibrin Lysate?" dans: Journal of stem cells & regenerative medicine, Vol. 15, Issue 1, pp. 3-7, (2019) (PubMed).

Elchaninov, Fatkhudinov, Makarov, Vorobieva, Lokhonina, Usman, Kananykhina, Vishnyakova, Nikitina, Goldshtein, Bolshakova, Glinkina, Sukhikh: "Inherent control of hepatocyte proliferation after subtotal liver resection." dans: Cell biology international, (2019) (PubMed).

Oh, Choi, Noh, Lee, Jeong, Jeon, Shin, Kim, Kim, Lee, Kim, Kim, Song: "Interleukin-1 receptor antagonist-mediated neuroprotection by umbilical cord-derived mesenchymal stromal cells following transplantation into a rodent stroke model." dans: Experimental & molecular medicine, Vol. 50, Issue 4, pp. 22, (2019) (PubMed).

Wang, Li, Zhu, Zhang, Li, Lin, Li, Zhu: "Overexpression of c-Met in bone marrow mesenchymal stem cells improves their effectiveness in homing and repair of acute liver failure." dans: Stem cell research & therapy, Vol. 8, Issue 1, pp. 162, (2018) (PubMed).

Guan, Qiao, Lv, Cao, Wang, Dai, Wei: "Orally administered berberine ameliorates bleomycin-induced pulmonary fibrosis in mice through promoting activation of PPAR-γ and subsequent expression of HGF in colons." dans: Toxicology and applied pharmacology, Vol. 343, pp. 1-15, (2018) (PubMed).

Synonymes et noms alternatifs relatifs à HGF

hepatocyte growth factor (HGF), hepatocyte growth factor (Hgf), C230052L06Rik, DFNB39, F-TCF, HGF, HGF/SF, HGFB, HPTA, NK1, NK2, SF, SF/HGF

Protein level used designations for HGF

  • fibroblast-derived tumor cytotoxic factor
  • hepatocyte growth factor
  • hepatopoeitin-A
  • hepatopoietin-A
  • lung fibroblast-derived mitogen
  • SF
  • scatter factor
  • hepapoietin A
  • HGF alpha-chain
  • hepatocyte growth factor /scatter factor
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