HIF1AN Produits
(Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN))
Catégories
This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011].
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Catégories HIF1AN en vedette
HIF1AN Anticorps
High quality antibodies with extensive validation data.
HIF1AN recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
N° du produit
ABIN7441979
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IP, IF
Validations
- (6)
N° du produit
ABIN527607
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IP, IF
Validations
- (5)
N° du produit
ABIN7156025
Quantité
100 μg
Fiche technique
Fiche technique
HIF1AN recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956649
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN454393
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1137714
Quantité
96 tests
Fiche technique
Fiche technique
HIF1AN recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1306622
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN3092929
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN3136220
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits HIF1AN
: "Myc-induced nuclear antigen constrains a latent intestinal epithelial cell-intrinsic anthelmintic pathway." dans: PLoS ONE, Vol. 14, Issue 2, pp. e0211244, (2019) (PubMed).: "Oxygen-dependent bond formation with FIH regulates the activity of the client protein OTUB1." dans: Redox biology, Vol. 26, pp. 101265, (2019) (PubMed).
: "Protein kinase A-dependent phosphorylation stimulates the transcriptional activity of hypoxia-inducible factor 1." dans: Science signaling, Vol. 9, Issue 430, pp. ra56, (2017) (PubMed).
: "miR-148a-3p Mediates Notch Signaling to Promote the Differentiation and M1 Activation of Macrophages." dans: Frontiers in immunology, Vol. 8, pp. 1327, (2017) (PubMed).
: "NECAB3 Promotes Activation of Hypoxia-inducible factor-1 during Normoxia and Enhances Tumourigenicity of Cancer Cells." dans: Scientific reports, Vol. 6, pp. 22784, (2016) (PubMed).
: "A DNA-binding Molecule Targeting the Adaptive Hypoxic Response in Multiple Myeloma Has Potent Antitumor Activity." dans: Molecular cancer research : MCR, Vol. 14, Issue 3, pp. 253-66, (2016) (PubMed).
: "Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel." dans: Journal of cell science, Vol. 128, Issue 2, pp. 225-31, (2015) (PubMed).
: "Factor-inhibiting HIF-1 (FIH-1) is required for human vascular endothelial cell survival." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 7, pp. 2814-27, (2015) (PubMed).
: "Expression and DNA methylation levels of prolyl hydroxylases PHD1, PHD2, PHD3 and asparaginyl hydroxylase FIH in colorectal cancer." dans: BMC cancer, Vol. 13, pp. 526, (2014) (PubMed).
: "Factor inhibiting HIF-1 (FIH-1) modulates protein interactions of apoptosis-stimulating p53 binding protein 2 (ASPP2)." dans: Journal of cell science, Vol. 126, Issue Pt 12, pp. 2629-40, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à HIF1AN
hypoxia inducible factor 1 alpha subunit inhibitor (HIF1AN), hypoxia-inducible factor 1, alpha subunit inhibitor (Hif1an), hypoxia inducible factor 1, alpha subunit inhibitor (hif1an), hypoxia-inducible factor 1, alpha subunit inhibitor S homeolog (hif1an.S), hypoxia inducible factor 1 alpha subunit inhibitor (Hif1an), 2310046M24Rik, A830014H24Rik, cb728, FIH1, id:ibd5139Protein level used designations for HIF1AN
- FIH-1
- factor inhibiting HIF-1
- factor inhibiting HIF1
- hypoxia-inducible factor 1-alpha inhibitor
- hypoxia-inducible factor asparagine hydroxylase
- peptide-aspartate beta-dioxygenase
- hypoxia-inducible factor 1, alpha subunit inhibitor
- LOW QUALITY PROTEIN: hypoxia-inducible factor 1-alpha inhibitor
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