HLA-DRA Produits
(HLA Class II DR alpha (HLA-DRA))
Catégories
HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq, Jul 2008].
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Catégories HLA-DRA en vedette
HLA-DRA Anticorps
High quality antibodies with extensive validation data.
HLA-DRA Kits ELISA
Reliable ELISA kits for a wide range of species.
HLA-DRA Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
HLA-DRA recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, FACS, ELISA, ICC
Validations
- (6)
N° du produit
ABIN5542623
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC
Validations
- (5)
N° du produit
ABIN6141827
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
N° du produit
ABIN7437542
Quantité
100 μL
Fiche technique
Fiche technique
HLA-DRA recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6974906
Quantité
96 tests
Fiche technique
Fiche technique
HLA-DRA recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN3092235
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3111639
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7401032
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits HLA-DRA
: "Comparison of the biological characteristics of human mesenchymal stem cells derived from exfoliated deciduous teeth, bone marrow, gingival tissue, and umbilical cord." dans: Molecular medicine reports, Vol. 18, Issue 6, pp. 4969-4977, (2019) (PubMed).: "Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition." dans: The Journal of clinical investigation, Vol. 126, Issue 8, pp. 3130-44, (2016) (PubMed).
: "Characterization and application of two RANK-specific antibodies with different biological activities." dans: Immunology letters, Vol. 171, pp. 5-14, (2016) (PubMed).
: "Dermal CD14(+) Dendritic Cell and Macrophage Infection by Dengue Virus Is Stimulated by Interleukin-4." dans: The Journal of investigative dermatology, Vol. 135, Issue 7, pp. 1743-51, (2015) (PubMed).
: "Involvement of the TNF-α/TGF-β/IDO axis in IVIg-induced immune tolerance." dans: Cytokine, Vol. 71, Issue 2, pp. 181-7, (2015) (PubMed).
: "Ex vivo tetramer staining and cell surface phenotyping for early activation markers CD38 and HLA-DR to enumerate and characterize malaria antigen-specific CD8+ T-cells induced in human volunteers ..." dans: Malaria journal, Vol. 12, pp. 376, (2014) (PubMed).
: "Down-regulation of complement receptors on the surface of host monocyte even as in vitro complement pathway blocking interferes in dengue infection." dans: PLoS ONE, Vol. 9, Issue 7, pp. e102014, (2014) (PubMed).
: "Vemurafenib enhances MHC induction in BRAF(V600E) homozygous melanoma cells." dans: Oncoimmunology, Vol. 2, Issue 1, pp. e22890, (2013) (PubMed).
: "Functional and molecular characterization of ex vivo cultured epiretinal membrane cells from human proliferative diabetic retinopathy." dans: BioMed research international, Vol. 2013, pp. 492376, (2013) (PubMed).
: "Efficient differentiation of human pluripotent stem cells into mesenchymal stem cells by modulating intracellular signaling pathways in a feeder/serum-free system." dans: Stem cells and development, Vol. 21, Issue 7, pp. 1165-75, (2012) (PubMed).
Synonymes et noms alternatifs relatifs à HLA-DRA
major histocompatibility complex, class II, DR alpha L homeolog (hla-dra.L), major histocompatibility complex, class II, DR alpha (HLA-DRA), major histocompatibility complex, class II, DR alpha (MAMU-DRA), major histocompatibility complex, class II, DR alpha (BOLA-DRA), DR-alpha, HLA-DRA, HLA-DRA1, Mamu-DRA1, MLRWProtein level used designations for HLA-DRA
- major histocompatibility complex, class II, DR alpha
- HLA class II histocompatibility antigen, DR alpha chain
- MHC cell surface glycoprotein
- MHC class II antigen DRA
- histocompatibility antigen HLA-DR alpha
- MHC class II DRA
- MHC class II antigen
- BoLA-DR-alpha
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