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HLA-DRA anticorps (AA 26-254)

HLA-DRA Reactivité: Humain WB, IHC, FACS, ELISA, ICC Hôte: Souris Monoclonal 1C11A5 unconjugated
N° du produit ABIN5542623
  • Antigène Voir toutes HLA-DRA Anticorps
    HLA-DRA (HLA Class II DR alpha (HLA-DRA))
    Épitope
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 26-254
    Reactivité
    • 89
    • 17
    • 10
    • 10
    • 9
    • 9
    • 3
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 57
    • 47
    • 1
    • 1
    Souris
    Clonalité
    • 57
    • 49
    Monoclonal
    Conjugué
    • 54
    • 12
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Cet anticorp HLA-DRA est non-conjugé
    Application
    • 48
    • 48
    • 35
    • 32
    • 17
    • 11
    • 11
    • 10
    • 9
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human HLA-DRA (AA: 26-254) expressed in E. coli.
    Clone
    1C11A5
    Isotype
    IgG2b
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: 1:100 - 1:500, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Antigène
    HLA-DRA (HLA Class II DR alpha (HLA-DRA))
    Autre désignation
    HLA-DRA (HLA-DRA Produits)
    Synonymes
    anticorps HLA-DRA1, anticorps MLRW, anticorps DR-alpha, anticorps HLA-DRA, anticorps Mamu-DRA1, anticorps major histocompatibility complex, class II, DR alpha L homeolog, anticorps major histocompatibility complex, class II, DR alpha, anticorps hla-dra.L, anticorps HLA-DRA, anticorps MAMU-DRA, anticorps BOLA-DRA
    Sujet

    Description: HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. ,

    Aliases: MLRW, HLA-DRA1

    Poids moléculaire
    28.6 kDa
    ID gène
    3122
    HGNC
    3858
    Pathways
    TCR Signaling, CXCR4-mediated Signaling Events
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