HTR2C Produits
(5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))
Catégories
Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines. RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in patterns of 5-HT2C editing in depressed suicide victims. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].
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Catégories HTR2C en vedette
HTR2C Anticorps
High quality antibodies with extensive validation data.
HTR2C Kits ELISA
Reliable ELISA kits for a wide range of species.
HTR2C Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
HTR2C recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (6)
N° du produit
ABIN2792274
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
N° du produit
ABIN6257909
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (3)
N° du produit
ABIN574008
Quantité
50 μL
Fiche technique
Fiche technique
HTR2C recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6953364
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5674799
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5674800
Quantité
96 tests
Fiche technique
Fiche technique
HTR2C recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7121620
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1307274
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3113303
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits HTR2C
: "Alcohol drives S-nitrosylation and redox activation of protein phosphatase 1, causing bovine airway cilia dysfunction." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 312, Issue 3, pp. L432-L439, (2017) (PubMed).: "An Orally Active Phenylaminotetralin-Chemotype Serotonin 5-HT7 and 5-HT1A Receptor Partial Agonist that Corrects Motor Stereotypy in Mouse Models." dans: ACS chemical neuroscience, Vol. 6, Issue 7, pp. 1259-70, (2015) (PubMed).
: "Involvement of spinal serotonin receptors in electroacupuncture anti-hyperalgesia in an inflammatory pain rat model." dans: Neurochemical research, Vol. 36, Issue 10, pp. 1785-92, (2011) (PubMed).
: "Activity Modes in Thalamocortical Relay Neurons are Modulated by G(q)/G(11) Family G-proteins - Serotonergic and Glutamatergic Signaling." dans: Frontiers in cellular neuroscience, Vol. 4, pp. 132, (2011) (PubMed).
: "Complex seizure disorder caused by Brunol4 deficiency in mice." dans: PLoS genetics, Vol. 3, Issue 7, pp. e124, (2007) (PubMed).
: "Serotonin receptor 2C (HTR2C) and schizophrenia: examination of possible medication and genetic influences on expression levels." dans: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 134B, Issue 1, pp. 84-9, (2005) (PubMed).
: "5-Hydroxytryptamine2C receptors on pudendal motoneurons innervating the external anal sphincter." dans: Brain research, Vol. 1057, Issue 1-2, pp. 65-71, (2005) (PubMed).
Synonymes et noms alternatifs relatifs à HTR2C
5-hydroxytryptamine receptor 2C (HTR2C), 5-hydroxytryptamine (serotonin) receptor 2C (Htr2c), 5-hydroxytryptamine receptor 2C (Htr2c), 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled S homeolog (htr2c.S), 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1 (htr2cl1), 5-hydroxytryptamine receptor 2C (LOC407134), 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled (HTR2C), 5-HT-2C, 5-HT2C, 5-HT2cR, 5-ht2cr, 5-HTR2C, 5HT-1C, 5HT1c, 5HT2C, 5ht2c, 5HTR2C, HTR1C, Htr1c, si:dkey-24g18.2, SR1Protein level used designations for HTR2C
- 5-HT-1C
- 5-HT-2C
- 5-HT1C
- 5-hydroxytryptamine receptor 1C
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor-1c
- serotonin 5-HT-2C receptor
- serotonin receptor 2C
- 5-HT2C receptor
- serotonin 1c receptor
- 5-hydroxytryptamine (serotonin) receptor 2C
- 5HT2C serotonin receptor
- 5-HT2C
- 5-alpha-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
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