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HTRA1 Produits

(HtrA Serine Peptidase 1 (HTRA1))
This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq, Jul 2008].

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Catégories HTRA1 en vedette

HTRA1 Anticorps

High quality antibodies with extensive validation data.

HTRA1 Kits ELISA

Reliable ELISA kits for a wide range of species.

HTRA1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HTRA1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, IF, IHC (p)
Validations
  • (1)
  • (4)
N° du produit ABIN388127
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application IHC, ELISA, IF
Validations
  • (3)
N° du produit ABIN7168916
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (2)
N° du produit ABIN388128
Quantité 400 μL
Fiche technique Fiche technique

HTRA1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6962019
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
N° du produit ABIN6960711
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967469
Quantité 96 tests
Fiche technique Fiche technique

HTRA1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3092982
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3137441
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7454132
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits HTRA1

Giannubilo, Licini, Picchiassi, Tarquini, Coata, Fantone, Tossetta, Ciavattini, Castellucci, Giardina, Gesuita, Marzioni: "First trimester HtrA1 maternal plasma level and spontaneous preterm birth." dans: The journal of maternal-fetal & neonatal medicine, pp. 1-5, (2020) (PubMed).

Beguier, Housset, Roubeix, Augustin, Zagar, Nous, Mathis, Eandi, Benchaboune, Drame-Maigné, Carpentier, Chardonnet, Touhami, Blot, Conart, Charles-Messance, Potey, Girmens, Paques, Blond, Leveillard et al.: "The 10q26 Risk Haplotype of Age-Related Macular Degeneration Aggravates Subretinal Inflammation by Impairing Monocyte Elimination. ..." dans: Immunity, Vol. 53, Issue 2, pp. 429-441.e8, (2020) (PubMed).

Lorenzi, Lorenzi, Marzetti, Landi, Vetrano, Settanni, Antocicco, Bonassi, Valdiglesias, Bernabei, Onder: "Association of frailty with the serine protease HtrA1 in older adults." dans: Experimental gerontology, Vol. 81, pp. 8-12, (2016) (PubMed).

Frochaux, Hildebrand, Talke, Linscheid, Schlüter: "Alpha-1-antitrypsin: a novel human high temperature requirement protease A1 (HTRA1) substrate in human placental tissue." dans: PLoS ONE, Vol. 9, Issue 10, pp. e109483, (2014) (PubMed).

Marzioni, Lorenzi, Altobelli, Giannubilo, Paolinelli, Tersigni, Crescimanno, Monsurrò, Tranquilli, Di Simone, Castellucci: "Alterations of maternal plasma HTRA1 level in preeclampsia complicated by IUGR." dans: Placenta, Vol. 33, Issue 12, pp. 1036-8, (2012) (PubMed).

Inagaki, Nishizawa, Ota, Suzuki, Inuzuka, Miyamura, Sekiya, Kurahashi, Udagawa: "Upregulation of HtrA4 in the placentas of patients with severe pre-eclampsia." dans: Placenta, Vol. 33, Issue 11, pp. 919-26, (2012) (PubMed).

Wang, Eckert, Zomorrodi, Xin, Pan, Shearer, Weisz, Maranus, Clawson: "Down-regulation of HtrA1 activates the epithelial-mesenchymal transition and ATM DNA damage response pathways." dans: PLoS ONE, Vol. 7, Issue 6, pp. e39446, (2012) (PubMed).

Shiga, Nozaki, Yokoseki, Nihonmatsu, Kawata, Kato, Koyama, Arima, Ikeda, Katada, Toyoshima, Takahashi, Tanaka, Nakano, Ikeuchi, Nishizawa, Onodera: "Cerebral small-vessel disease protein HTRA1 controls the amount of TGF-β1 via cleavage of proTGF-β1." dans: Human molecular genetics, Vol. 20, Issue 9, pp. 1800-10, (2011) (PubMed).

Chamberland, Wang, Jones, Collins-Racie, LaVallie, Huang, Liu, Morris, Flannery, Yang: "Identification of a novel HtrA1-susceptible cleavage site in human aggrecan: evidence for the involvement of HtrA1 in aggrecan proteolysis in vivo." dans: The Journal of biological chemistry, Vol. 284, Issue 40, pp. 27352-9, (2009) (PubMed).

Clawson, Bui, Xin, Wang, Pan: "Intracellular localization of the tumor suppressor HtrA1/Prss11 and its association with HPV16 E6 and E7 proteins." dans: Journal of cellular biochemistry, Vol. 105, Issue 1, pp. 81-8, (2008) (PubMed).

Synonymes et noms alternatifs relatifs à HTRA1

HtrA serine peptidase 1a (htra1a), HtrA serine peptidase 1 (HTRA1), HtrA serine peptidase 1b (htra1b), HtrA serine peptidase 1 (htra1), Serine protease HTRA1 (htra1), HtrA serine peptidase 1 (Htra1), HtrA serine peptidase 1 S homeolog (htra1.S), AI429470, ARMD7, CARASIL, htra, HtrA, HTRA, htra1, HTRA1, l56, L56, MGC145723, ORF480, prss11, PRSS11, Prss11, RSPP11, Xhtra1, zgc:92029, zgc:172061

Protein level used designations for HTRA1

  • HtrA serine peptidase 1
  • high-temperature requirement A serine peptidase 1A
  • serine protease 11
  • serine protease HTRA1A
  • high-temperature requirement A serine peptidase 1B
  • serine protease HTRA1B
  • high temperature required A1
  • Serine protease HTRA1
  • IGFBP5-protease
  • high-temperature requirement A serine peptidase 1
  • protease, serine, 11 (IGF binding)
  • serine protease HTRA1
  • insulin-like growth factor binding protein 5 protease
  • protease, serine, 11 (Igf binding)
  • IGF binding
  • protease, serine, 11
  • protease serine 11
  • High-temperature requirement A serine peptidase 1
  • Serine protease 11
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