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HTRA3 Produits

(HtrA Serine Peptidase 3 (HTRA3))
Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (By similarity). May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization (By similarity).

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Catégories HTRA3 en vedette

HTRA3 Anticorps

High quality antibodies with extensive validation data.

HTRA3 Kits ELISA

Reliable ELISA kits for a wide range of species.

HTRA3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HTRA3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Rat
Application WB, IHC (p)
Validations
  • (3)
  • (4)
N° du produit ABIN1882095
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (3)
N° du produit ABIN949792
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application IHC, ELISA
Validations
  • (1)
N° du produit ABIN7238582
Quantité 200 μL
Fiche technique Fiche technique

HTRA3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN512526
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Pig
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN779001
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Chicken
Analytical Method Competition ELISA
Validations
N° du produit ABIN1054750
Quantité 96 tests
Fiche technique Fiche technique

HTRA3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (3)
N° du produit ABIN3092994
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123367
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1307287
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits HTRA3

Dynon, Heng, Puryer, Li, Walton, Endo, Nie: "HtrA3 as an early marker for preeclampsia: specific monoclonal antibodies and sensitive high-throughput assays for serum screening." dans: PLoS ONE, Vol. 7, Issue 9, pp. e45956, (2012) (PubMed).

Beleford, Rattan, Chien, Shridhar: "High temperature requirement A3 (HtrA3) promotes etoposide- and cisplatin-induced cytotoxicity in lung cancer cell lines." dans: The Journal of biological chemistry, Vol. 285, Issue 16, pp. 12011-27, (2010) (PubMed).

Narkiewicz, Klasa-Mazurkiewicz, Zurawa-Janicka, Skorko-Glonek, Emerich, Lipinska: "Changes in mRNA and protein levels of human HtrA1, HtrA2 and HtrA3 in ovarian cancer." dans: Clinical biochemistry, Vol. 41, Issue 7-8, pp. 561-9, (2008) (PubMed).

Grau, Baldi, Bussani, Tian, Stefanescu, Przybylski, Richards, Jones, Shridhar, Clausen, Ehrmann: "Implications of the serine protease HtrA1 in amyloid precursor protein processing." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 17, pp. 6021-6, (2005) (PubMed).

Nie, Hampton, Li, Findlay, Salamonsen et al.: "Identification and cloning of two isoforms of human high-temperature requirement factor A3 (HtrA3), characterization of its genomic structure and comparison of its tissue distribution with HtrA1 and ..." dans: The Biochemical journal, Vol. 371, Issue Pt 1, pp. 39-48, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à HTRA3

Trypsin-like serine protease (htrA3), HtrA serine peptidase 3 (HTRA3), HtrA serine peptidase 3 (Htra3), 2210021K23Rik, 9530081K03Rik, HTRA3, Prsp, RGD1308120, Tasp

Protein level used designations for HTRA3

  • Trypsin-like serine protease
  • HtrA serine peptidase 3
  • probable serine protease HTRA3-like
  • high-temperature requirement factor A3
  • pregnancy-related serine protease
  • probable serine protease HTRA3
  • serine protease HTRA3
  • toll-associated serine protease
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