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HVEM Produits

(Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))

Catégories

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response. [provided by RefSeq, Jul 2008].

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Catégories HVEM en vedette

HVEM Anticorps

High quality antibodies with extensive validation data.

HVEM Kits ELISA

Reliable ELISA kits for a wide range of species.

HVEM Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HVEM recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (5)
N° du produit ABIN563772
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
N° du produit ABIN653038
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
N° du produit ABIN7443230
Quantité 100 μL
Fiche technique Fiche technique

HVEM recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970979
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1889390
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1889391
Quantité 96 tests
Fiche technique Fiche technique

HVEM recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (6)
N° du produit ABIN7274831
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
N° du produit ABIN7274832
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (3)
N° du produit ABIN4949111
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits HVEM

Szymczak, Ziętkiewicz, Kuncewicz, Rodziewicz-Motowidło, Orlikowska: "Expression, purification, and efficient refolding of the extracellular domain of Escherichia coli-expressed signaling receptor herpesvirus entry mediator." dans: Protein expression and purification, Vol. 164, pp. 105450, (2019) (PubMed).

Kuncewicz, Spodzieja, Sieradzan, Karczyńska, Dąbrowska, Dadlez, Speiser, Derre, Rodziewicz-Motowidło: "A structural model of the immune checkpoint CD160-HVEM complex derived from HDX-mass spectrometry and molecular modeling." dans: Oncotarget, Vol. 10, Issue 4, pp. 536-550, (2019) (PubMed).

Abadpour, Halvorsen, Sahraoui, Korsgren, Aukrust, Scholz: "Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT." dans: Journal of molecular endocrinology, Vol. 60, Issue 3, pp. 171-183, (2018) (PubMed).

de Mare-Bredemeijer, Shi, Mancham, van Gent, van der Heide-Mulder, de Boer, Heemskerk, de Jonge, van der Laan, Metselaar, Kwekkeboom: "Cytomegalovirus-Induced Expression of CD244 after Liver Transplantation Is Associated with CD8+ T Cell Hyporesponsiveness to Alloantigen." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 4, pp. 1838-48, (2015) (PubMed).

Connor, Felder, Kapur, Onujiogu: "DcR3 binds to ovarian cancer via heparan sulfate proteoglycans and modulates tumor cells response to platinum with corresponding alteration in the expression of BRCA1." dans: BMC cancer, Vol. 12, pp. 176, (2012) (PubMed).

Cheung, Oborne, Steinberg, Macauley, Fukuyama, Sanjo, DSouza, Norris, Pfeffer, Murphy, Kronenberg, Spear, Ware: "T cell intrinsic heterodimeric complexes between HVEM and BTLA determine receptivity to the surrounding microenvironment." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 11, pp. 7286-96, (2009) (PubMed).

Wang, Wen, Routy, Bernard, Sekaly, Watts et al.: "4-1BBL induces TNF receptor-associated factor 1-dependent Bim modulation in human T cells and is a critical component in the costimulation-dependent rescue of functionally impaired HIV-specific CD8 T ..." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 12, pp. 8252-63, (2007) (PubMed).

Kang, Kim, Kang, Han, Nam, Kyung, Park, Kim: "LIGHT up-regulated on B lymphocytes and monocytes in rheumatoid arthritis mediates cellular adhesion and metalloproteinase production by synoviocytes." dans: Arthritis and rheumatism, Vol. 56, Issue 4, pp. 1106-17, (2007) (PubMed).

Watts: "TNF/TNFR family members in costimulation of T cell responses." dans: Annual review of immunology, Vol. 23, pp. 23-68, (2005) (PubMed).

Cheung, Humphreys, Potter, Norris, Shumway, Tran, Patterson, Jean-Jacques, Yoon, Spear, Murphy, Lurain, Benedict, Ware: "Evolutionarily divergent herpesviruses modulate T cell activation by targeting the herpesvirus entry mediator cosignaling pathway." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 37, pp. 13218-23, (2005) (PubMed).

Synonymes et noms alternatifs relatifs à HVEM

TNF receptor superfamily member 14 (Tnfrsf14), TNF receptor superfamily member 14 (TNFRSF14), tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (Tnfrsf14), ATAR, Atar, CD270, HVEA, HveA, HVEM, Hvem, LIGHTR, Tnfrs14, TR2

Protein level used designations for HVEM

  • tumor necrosis factor receptor superfamily member 14
  • tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
  • herpesvirus entry mediator A
  • CD40-like protein
  • herpes virus entry mediator A
  • tumor necrosis factor receptor-like 2
  • tumor necrosis factor receptor-like gene2
  • herpes virus entry mediator
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