IL-7 Protéines
(Interleukin 7 (IL7))
The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.[provided by RefSeq, Dec 2010].
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64 Résultats
IL7
Origine: Souris
Hôte: CHO Cells
Recombinant
> 95 % as analyzed by SDS-PAGE.
Active
IL7
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
1 image
IL7
Origine: Rat
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
Active
1 image
IL7
Origine: Rat
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 85 % as determined by SDS-PAGE.
1 image
IL7
Origine: Humain
Hôte: Wheat germ
Recombinant
AP, AA, ELISA, WB
1 image
IL7
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
CC
Active
1 image
GMP Grade
IL7
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
>95 %
WB
Active
1 image
IL7
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
AcA, CC
Active
3 images
IL7
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
>90 % as determined by SDS-PAGE.
WB, SDS, Imm, ELISA, AcA
Active
IL7
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
IL7
Origine: Humain
Hôte: CHO Cells
Recombinant
>98 % (SDS-PAGE)
Active
IL7
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
Active
IL7
Origine: Humain
Hôte: Escherichia coli (E. coli)
> 95 % by SDS-PAGE and HPLC analyses.
Active
IL7
Origine: Rat
Hôte: Escherichia coli (E. coli)
Recombinant
>95 % , as determined by SDS-PAGE and HPLC
Active
IL7
Origine: Humain
Hôte: Baculovirus infected Insect Cells
Recombinant
> 90 %
SDS, AcA
Active
IL7
Origine: Humain
Hôte: Baculovirus infected Insect Cells
Recombinant
> 90 %
SDS
IL7
Origine: Humain
Hôte: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Dernières publications pour nos IL-7 Protéines
: "gp96, an endoplasmic reticulum master chaperone for integrins and Toll-like receptors, selectively regulates early T and B lymphopoiesis." dans: Blood, Vol. 115, Issue 12, pp. 2380-90, (2010) (PubMed).
: "Ikaros regulates Notch target gene expression in developing thymocytes." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 9, pp. 6265-74, (2008) (PubMed).
: "Interleukin-7: a new hematopoietic growth factor." dans: Progress in clinical and biological research, Vol. 338, pp. 65-73, (1990) (PubMed).
: "Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 1, pp. 302-6, (1989) (PubMed).
: "Isolation and characterization of a human interleukin cDNA clone, homologous to mouse B-cell stimulatory factor 1, that expresses B-cell- and T-cell-stimulating activities." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 16, pp. 5894-8, (1986) (PubMed).
: "Ikaros regulates Notch target gene expression in developing thymocytes." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 9, pp. 6265-74, (2008) (PubMed).
: "Interleukin-7: a new hematopoietic growth factor." dans: Progress in clinical and biological research, Vol. 338, pp. 65-73, (1990) (PubMed).
: "Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 1, pp. 302-6, (1989) (PubMed).
: "Isolation and characterization of a human interleukin cDNA clone, homologous to mouse B-cell stimulatory factor 1, that expresses B-cell- and T-cell-stimulating activities." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 16, pp. 5894-8, (1986) (PubMed).
Pseudonymes pour IL-7 Protéines
interleukin 7 (IL7) Protéinesinterleukin 7 (Il7) Protéines
A630026I06Rik Protéines
hlb368 Protéines
IL-7 Protéines
Il-7 Protéines
IL7 Protéines
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