IL15RA Produits
(Interleukin 15 Receptor, alpha (IL15RA))
Catégories
This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.[provided by RefSeq, Apr 2010].
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Catégories IL15RA en vedette
IL15RA Anticorps
High quality antibodies with extensive validation data.
IL15RA Kits ELISA
Reliable ELISA kits for a wide range of species.
IL15RA Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
IL15RA recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, Neut, ICC
Validations
- (4)
N° du produit
ABIN7193409
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (3)
N° du produit
ABIN1680439
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
ELISA, IHC
Validations
- (2)
N° du produit
ABIN7242230
Quantité
200 μL
Fiche technique
Fiche technique
IL15RA recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6967877
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6967876
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN2703178
Quantité
96 tests
Fiche technique
Fiche technique
IL15RA recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7275020
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7274956
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7274957
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits IL15RA
: "NK Cells Require Cell-Extrinsic and -Intrinsic TYK2 for Full Functionality in Tumor Surveillance and Antibacterial Immunity." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 202, Issue 6, pp. 1724-1734, (2019) (PubMed).: "Rheumatoid arthritis bone marrow environment supports Th17 response." dans: Arthritis research & therapy, Vol. 19, Issue 1, pp. 274, (2018) (PubMed).
: "IL-15 signaling promotes adoptive effector T-cell survival and memory formation in irradiation-induced lymphopenia." dans: Cell & bioscience, Vol. 6, pp. 30, (2016) (PubMed).
: "IL-18Rα-deficient CD4(+) T cells induce intestinal inflammation in the CD45RB(hi) transfer model of colitis despite impaired innate responsiveness." dans: European journal of immunology, Vol. 46, Issue 6, pp. 1371-82, (2016) (PubMed).
: "IL-15 receptor α signaling constrains the development of IL-17-producing γδ T cells." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 31, pp. 9692-7, (2015) (PubMed).
: "Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1β, IFN-β, and IL-15 Pathways." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 6, pp. 2818-28, (2015) (PubMed).
: "Intramuscular delivery of heterodimeric IL-15 DNA in macaques produces systemic levels of bioactive cytokine inducing proliferation of NK and T cells." dans: Gene therapy, Vol. 22, Issue 1, pp. 76-86, (2015) (PubMed).
: "Interleukin-15 and soluble interleukin-15 receptor ? in coronary artery disease patients: association with epicardial fat and indices of adipose tissue distribution." dans: PLoS ONE, Vol. 9, Issue 3, pp. e90960, (2014) (PubMed).
: "Anti-inflammatory cytokines directly inhibit innate but not adaptive CD8+ T cell functions." dans: Journal of virology, Vol. 88, Issue 13, pp. 7474-84, (2014) (PubMed).
: "Regulation of CD4(+)NKG2D(+) Th1 cells in patients with metastatic melanoma treated with sorafenib: role of IL-15Rα and NKG2D triggering. ..." dans: Cancer research, Vol. 74, Issue 1, pp. 68-80, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à IL15RA
interleukin 15 receptor subunit alpha (IL15RA), interleukin 15 receptor subunit alpha (Il15ra), interleukin 15 receptor, alpha chain (Il15ra), AA690181, CD215, IL-15RA, IL15RAProtein level used designations for IL15RA
- interleukin-15 receptor subunit alpha
- interleukin 15 receptor alpha
- interleukin 15 receptor, alpha
- interleukin 15 receptor, alpha chain
- IL-15 receptor subunit alpha
- IL-15R-alpha
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