IMPDH2 Protein (AA 1-514) (His tag)

N° du produit ABIN667973

Détail du produit

Antigène: IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))

Type de proteíne: Recombinant

Attributs du protein: AA 1-514

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette IMPDH2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: IMPDH2, 1-514aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 150mM NaCl

Stock: 4 °C

Détail du antigène

Antigène: IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))

Autre désignation: IMPDH2 (IMPDH2 Produits)

Synonymes: imp2 Protein, impd2 Protein, impdh-ii Protein, impdh2 Protein, IMPD2 Protein, IMPDH-II Protein, IMPD 2 Protein, IMPDH 2 Protein, cb635 Protein, wu:fb64g02 Protein, wu:fc43f09 Protein, IMPD Protein, inosine monophosphate dehydrogenase 2 Protein, IMP (inosine 5'-monophosphate) dehydrogenase 2 Protein, inosine 5'-phosphate dehydrogenase 2 Protein, IMPDH2 Protein, impdh2.S Protein, impdh2 Protein, Impdh2 Protein

Sujet: IMPDH2 belongs to the IMPDH/GMPR family. It catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. Also IMPDH1 and IMPDH2 are targets for the important immunosuppressive drug, mycophenolic acid (MPA). Recombinant human IMPDH2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Inosine-5'-monophosphate dehydrogenase 2, IMPD2, IMPDH-II. NCBI no.: NP_000875

Poids moléculaire: 58.0kDa (534aa)

Pathways: Ribonucleoside Biosynthetic Process, SARS-CoV-2 Protein Interactome