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IRF9 Produits

(Interferon Regulatory Factor 9 (IRF9))

Catégories

Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

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Catégories IRF9 en vedette

IRF9 Anticorps

High quality antibodies with extensive validation data.

IRF9 Kits ELISA

Reliable ELISA kits for a wide range of species.

IRF9 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

IRF9 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF
Validations
  • (6)
N° du produit ABIN3031426
Quantité 0.4 mL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IF, IHC (p)
Validations
  • (4)
N° du produit ABIN655818
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application IF, FACS
Validations
  • (4)
N° du produit ABIN7504160
Quantité 100 μg
Fiche technique Fiche technique

IRF9 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6956915
Quantité 96 tests
Fiche technique Fiche technique

IRF9 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123501
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1308102
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3082016
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits IRF9

Assetta, De Cecco, OHara, Atwood: "JC Polyomavirus Infection of Primary Human Renal Epithelial Cells Is Controlled by a Type I IFN-Induced Response." dans: mBio, Vol. 7, Issue 4, (2016) (PubMed).

Kyriakidis, Kapsogeorgou, Gourzi, Konsta, Baltatzis, Tzioufas: "Toll-like receptor 3 stimulation promotes Ro52/TRIM21 synthesis and nuclear redistribution in salivary gland epithelial cells, partially via type I interferon pathway." dans: Clinical and experimental immunology, Vol. 178, Issue 3, pp. 548-60, (2014) (PubMed).

Bidwell, Slaney, Withana, Forster, Cao, Loi, Andrews, Mikeska, Mangan, Samarajiwa, de Weerd, Gould, Argani, Möller, Smyth, Anderson, Hertzog, Parker: "Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape." dans: Nature medicine, Vol. 18, Issue 8, pp. 1224-31, (2013) (PubMed).

Subba-Reddy, Goodfellow, Kao: "VPg-primed RNA synthesis of norovirus RNA-dependent RNA polymerases by using a novel cell-based assay." dans: Journal of virology, Vol. 85, Issue 24, pp. 13027-37, (2011) (PubMed).

Schumacher, Lau, Johnson: "Structural basis of core promoter recognition in a primitive eukaryote." dans: Cell, Vol. 115, Issue 4, pp. 413-24, (2003) (PubMed).

Dumler, Kopmann, Wagner, Mayboroda, Jerke, Dietz, Haller, Gulba: "Urokinase induces activation and formation of Stat4 and Stat1-Stat2 complexes in human vascular smooth muscle cells." dans: The Journal of biological chemistry, Vol. 274, Issue 34, pp. 24059-65, (1999) (PubMed).

Köster, Hauser: "Dynamic redistribution of STAT1 protein in IFN signaling visualized by GFP fusion proteins." dans: European journal of biochemistry / FEBS, Vol. 260, Issue 1, pp. 137-44, (1999) (PubMed).

Veals, Schindler, Leonard, Fu, Aebersold, Darnell, Levy: "Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins." dans: Molecular and cellular biology, Vol. 12, Issue 8, pp. 3315-24, (1992) (PubMed).

Synonymes et noms alternatifs relatifs à IRF9

interferon regulatory factor 9 (IRF9), interferon regulatory factor 9 (irf9), interferon regulatory factor 9 (Irf9), IRF-9, Irf-9, ISGF3, ISGF3G, Isgf3g, p48, zgc:92097

Protein level used designations for IRF9

  • interferon regulatory factor 9
  • interferon-stimulated transcription factor 3, gamma 48kDa
  • IFN-alpha-responsive transcription factor subunit
  • ISGF-3 gamma
  • ISGF3 p48 subunit
  • interferon-stimulated gene factor 3 gamma
  • interferon-stimulated transcription factor 3, gamma (48kD)
  • transcriptional regulator ISGF3 subunit gamma
  • interferon dependent positive acting transcription factor 3 gamma
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