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IRS2 Produits

(Insulin Receptor Substrate 2 (IRS2))
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq, Jul 2008].

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Catégories IRS2 en vedette

IRS2 Anticorps

High quality antibodies with extensive validation data.

IRS2 Kits ELISA

Reliable ELISA kits for a wide range of species.

IRS2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

IRS2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
N° du produit ABIN7443698
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7156336
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application ELISA, WB, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
  • (2)
N° du produit ABIN725840
Quantité 100 μL
Fiche technique Fiche technique

IRS2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6956772
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967616
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6956770
Quantité 96 tests
Fiche technique Fiche technique

IRS2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123447
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1308108
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3093121
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits IRS2

Głombik, Ślusarczyk, Trojan, Chamera, Budziszewska, Lasoń, Basta-Kaim: "Regulation of insulin receptor phosphorylation in the brains of prenatally stressed rats: New insight into the benefits of antidepressant drug treatment." dans: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, Vol. 27, Issue 2, pp. 120-131, (2017) (PubMed).

Wang, Wang, Zhang, Lin, Liu, Xiao, Xiao, Wang: "Defective insulin signaling and the protective effects of dimethyldiguanide during follicular development in the ovaries of polycystic ovary syndrome." dans: Molecular medicine reports, Vol. 16, Issue 6, pp. 8164-8170, (2017) (PubMed).

Ling, Xie, Li, Liu, Cao, Yang, Wang, Hu, Xu, Zheng: "Donor Graft MicroRNAs: A Newly Identified Player in the Development of New-onset Diabetes After Liver Transplantation." dans: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, Vol. 17, Issue 1, pp. 255-264, (2016) (PubMed).

Liu, You, Weng, Wei, Eng, Huang: "Recurrent Amplification at 13q34 Targets at CUL4A, IRS2, and TFDP1 As an Independent Adverse Prognosticator in Intrahepatic Cholangiocarcinoma." dans: PLoS ONE, Vol. 10, Issue 12, pp. e0145388, (2015) (PubMed).

Dearth, Cui, Kim, Hadsell, Lee: "Oncogenic transformation by the signaling adaptor proteins insulin receptor substrate (IRS)-1 and IRS-2." dans: Cell cycle (Georgetown, Tex.), Vol. 6, Issue 6, pp. 705-13, (2007) (PubMed).

Li, Soos, Li, Wu, Degennaro, Sun, Littman, Birnbaum, Polakiewicz: "Protein kinase C Theta inhibits insulin signaling by phosphorylating IRS1 at Ser(1101)." dans: The Journal of biological chemistry, Vol. 279, Issue 44, pp. 45304-7, (2004) (PubMed).

White: "IRS proteins and the common path to diabetes." dans: American journal of physiology. Endocrinology and metabolism, Vol. 283, Issue 3, pp. E413-22, (2002) (PubMed).

Burks, White: "IRS proteins and beta-cell function." dans: Diabetes, Vol. 50 Suppl 1, pp. S140-5, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à IRS2

insulin receptor substrate 2 (IRS2), insulin receptor substrate 2a (irs2a), insulin receptor substrate 2b (irs2b), insulin receptor substrate 2 (Irs2), 4PS, IRS-2, Irs-2, IRS2, si:dkeyp-24d6.1

Protein level used designations for IRS2

  • insulin receptor substrate 2
  • tyrosine kinase substrate
  • 4PS
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