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IRF3 Produits

(Interferon Regulatory Factor 3 (IRF3))

Catégories

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011].

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Catégories IRF3 en vedette

IRF3 Anticorps

High quality antibodies with extensive validation data.

IRF3 Kits ELISA

Reliable ELISA kits for a wide range of species.

IRF3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

IRF3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Monkey, Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro)
Validations
  • (4)
  • (5)
N° du produit ABIN742688
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (6)
N° du produit ABIN7260265
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF, ChIP
Validations
  • (1)
  • (5)
N° du produit ABIN6142528
Quantité 100 μL
Fiche technique Fiche technique

IRF3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6956910
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
  • (3)
N° du produit ABIN5691022
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967754
Quantité 96 tests
Fiche technique Fiche technique

IRF3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (4)
  • (1)
N° du produit ABIN1308082
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123496
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1308084
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits IRF3

Sprokholt, Kaptein, van Hamme, Overmars, Gringhuis, Geijtenbeek: "RIG-I-like receptor activation by dengue virus drives follicular T helper cell formation and antibody production." dans: PLoS pathogens, Vol. 13, Issue 11, pp. e1006738, (2018) (PubMed).

Wang, Sun, Yi, Zhang, Lin, Sun, Chen, Jin: "AGO2 Negatively Regulates Type I Interferon Signaling Pathway by Competition Binding IRF3 with CBP/p300." dans: Frontiers in cellular and infection microbiology, Vol. 7, pp. 195, (2018) (PubMed).

Ando, Matsumoto, Taguchi, Kobayashi: "Poly (I:C) impairs NO donor-induced relaxation by overexposure to NO via the NF-kappa B/iNOS pathway in rat superior mesenteric arteries." dans: Free radical biology & medicine, Vol. 112, pp. 553-566, (2017) (PubMed).

Yu, Wang, He, Wang, Gao, Ren, Shi et al.: "Curcumin exerts anti-inflammatory and antioxidative properties in 1-methyl-4-phenylpyridinium ion (MPP(+))-stimulated mesencephalic astrocytes by interference with TLR4 and downstream signaling ..." dans: Cell stress & chaperones, Vol. 21, Issue 4, pp. 697-705, (2017) (PubMed).

Zhu, Wang, Pei, Wang, Wu, Qiu, Zhang, Lv, Li, Zhang: "Neddylation controls basal MKK7 kinase activity in breast cancer cells." dans: Oncogene, Vol. 35, Issue 20, pp. 2624-33, (2017) (PubMed).

Ye, Chen, Li, Zhao, He, Zohaib, Song, Deng, Zhang, Chen, Cao: "Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-κB." dans: Journal of virology, Vol. 91, Issue 8, (2017) (PubMed).

Qian, Fan, Liu, Wu, Zhang, Cui, Zhou, Hu, Wei, Chen, Li, Qian: "Seneca Valley Virus Suppresses Host Type I Interferon Production by Targeting Adaptor Proteins MAVS, TRIF, and TANK for Cleavage." dans: Journal of virology, Vol. 91, Issue 16, (2017) (PubMed).

Fan, Li, Zhu, Sui, Chen, Deng, Sui, Wang: "NF-κB is involved in the LPS-mediated proliferation and apoptosis of MAC-T epithelial cells as part of the subacute ruminal acidosis response in cows." dans: Biotechnology letters, Vol. 38, Issue 11, pp. 1839-1849, (2016) (PubMed).

Pourcelot, Zemirli, Silva Da Costa, Loyant, Garcin, Vitour, Munitic, Vazquez, Arnoult: "The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing." dans: BMC biology, Vol. 14, pp. 69, (2016) (PubMed).

Zhang, Wang, Zhong, Luo, Shang, Liu, Chen, Fang, Xiao: "Ubiquitin-specific Protease 15 Negatively Regulates Virus-induced Type I Interferon Signaling via Catalytically-dependent and -independent Mechanisms." dans: Scientific reports, Vol. 5, pp. 11220, (2016) (PubMed).

Synonymes et noms alternatifs relatifs à IRF3

interferon regulatory factor 3 (irf3), interferon regulatory factor 3 (IRF3), interferon regulatory factor 3 (irf-3), interferon regulatory factor 3 (Irf3), interferon regulatory factor 7 (IRF7), C920001K05Rik, IRF-3, irf3, IRF3

Protein level used designations for IRF3

  • interferon regulatory factor 3
  • interferon regulatory factor 3-like
  • IRF-3
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