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Caspase 1 Kit ELISA

Ce kit ELISA Souris Caspase 1 est un kit ELISA Colorimetric conçu pour quantifier Souris Caspase 1. Ce Kit ELISA a été cité dans 1 publication.
N° du produit ABIN1168983

Aperçu rapide pour Caspase 1 Kit ELISA (ABIN1168983)

Antigène

Voir toutes Caspase 1 (CASP1) Kits ELISA
Caspase 1 (CASP1)

Reactivité

  • 6
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Souris

Méthode de détection

Colorimetric

Type de méthode

Sandwich ELISA

Gamme de detection

0.15-10 ng/mL

Application

ELISA

Type d'échantillon

Cell Culture Supernatant, Plasma, Serum
  • Seuil minimal de détection

    0.15 ng/mL

    Analytical Method

    Quantitative

    Specificité

    Detects mouse caspase-1 (proform as well as p10 and p20 domain).

     Réactivité croisée

    Souris

    Réactivité croisée (Details)

    Does not detect human caspase-1.

    Sensibilité

    33 pg/mL

    Attributs du produit

    Standards are full lenght proteins.
  • Plaque

    Pre-coated

    Restrictions

    For Research Use only
  • Conseil sur la manipulation

    Avoid freeze/thaw cycles. Plate and reagents should reach room temperature before use.

    Stock

    4 °C

    Stockage commentaire

    After standard reconstitution prepare aliquots and store at -20°C.

    Date de péremption

    12 months
  • Miyazaki, Mihara, Inata, Sasaki, Tominaga, Yakura, Ishida, Fukushima, Inoue: "Pharmacologic inhibition of IκB kinase activates immediate hypersensitivity reactions in mice." dans: The American journal of pathology, Vol. 183, Issue 1, pp. 96-107, (2013) (PubMed).

  • Antigène Voir toutes Caspase 1 (CASP1) Kits ELISA

    Caspase 1 (CASP1)

    Autre désignation

    Caspase-1

    Sujet

    Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and interleukin-18 (IL-18) and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3/NALP3 responds to a variety of agonists including crystals._x000D__x000D_This Caspase-1 (mouse) ELISA Kit can be used to measure caspase-1 (mouse) in cell culture supernatants. It is a quantitative detection method, alternative to Western blotting to measure caspase-1 secretion.

    UniProt

    P29452

    Pathways

    Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
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