Caspase 1 Kit ELISA

N° du produit ABIN1168983

Détail du produit Caspase 1 Kit ELISA

Antigène: Caspase 1 (CASP1)

Reactivité: Souris

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 0.15-10 ng/mL

Seuil minimal de détection: 0.15 ng/mL

Application: ELISA

Type d'échantillon: Cell Culture Supernatant, Plasma, Serum

Analytical Method: Quantitative

Specificité: Detects mouse caspase-1 (proform as well as p10 and p20 domain).

Réactivité croisée: Souris

Réactivité croisée (Details): Does not detect human caspase-1.

Sensibilité: 33 pg/mL

Attributs du produit: Standards are full lenght proteins.

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Conseil sur la manipulation: Avoid freeze/thaw cycles. Plate and reagents should reach room temperature before use.

Stock: 4 °C

Stockage commentaire: After standard reconstitution prepare aliquots and store at -20°C.

Date de péremption: 12 months

Références pour Caspase 1 Kit ELISA (ABIN1168983)

Miyazaki, Mihara, Inata, Sasaki, Tominaga, Yakura, Ishida, Fukushima, Inoue: "Pharmacologic inhibition of IκB kinase activates immediate hypersensitivity reactions in mice." dans: The American journal of pathology, Vol. 183, Issue 1, pp. 96-107, (2013) (PubMed).

Détail du antigène

Antigène: Caspase 1 (CASP1)

Autre désignation: Caspase-1 (CASP1 Produits)

Synonymes: ICE Kit ELISA, IL1BC Kit ELISA, P45 Kit ELISA, Il1bc Kit ELISA, Ice Kit ELISA, CASP1 Kit ELISA, CG5370 Kit ELISA, DCP-1 Kit ELISA, DCP1 Kit ELISA, Dcp1 Kit ELISA, Dmel\\CG5370 Kit ELISA, ccp1 Kit ELISA, dcp-1 Kit ELISA, dcp1 Kit ELISA, l(2)01862 Kit ELISA, l(2)02132 Kit ELISA, caspase 1 Kit ELISA, caspase 1, apoptosis-related cysteine peptidase Kit ELISA, caspase 4, apoptosis-related cysteine peptidase Kit ELISA, Death caspase-1 Kit ELISA, caspase-1 Kit ELISA, caspase Kit ELISA, caspase recruitment domain-containing protein 16 Kit ELISA, caspase 4 Kit ELISA, CASP1 Kit ELISA, Casp1 Kit ELISA, CASP4 Kit ELISA, Dcp-1 Kit ELISA, Caspase1 Kit ELISA, LOC5564196 Kit ELISA, LOC451519 Kit ELISA

Sujet: Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and interleukin-18 (IL-18) and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3/NALP3 responds to a variety of agonists including crystals._x000D__x000D_This Caspase-1 (mouse) ELISA Kit can be used to measure caspase-1 (mouse) in cell culture supernatants. It is a quantitative detection method, alternative to Western blotting to measure caspase-1 secretion.

UniProt: P29452

Pathways: Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome