CXCL2 Kit ELISA
Aperçu rapide pour CXCL2 Kit ELISA (ABIN2648786)
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Méthode de détection
Application
Type d'échantillon
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Fonction
- Rat Macrophage inflammatory protein-2 (MIP-2) ELISA Assay Kit (enzyme-linked immunoassay kit) is intended for the quantitative determination of rat macrophage inflammatory protein-2 (MIP-2 ) concentrations in cell culture supernates, serum, and plasma.
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Analytical Method
- Quantitative
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Attributs du produit
- Rat Macrophage inflammatory protein-2 (MIP-2) ELISA Assay Kit is for research use only and not to be used in diagnostic procedures.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Durée du test
- 3.5 h
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Plaque
- Pre-coated
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Protocole
- Macrophage inflammatory protein-2(MIP-2) was originally identified as a heparin binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The protein is produced by a variety of cell types, including intestinal epithelium, macrophages, astrocytes and fibroblasts. Homologs of the mouse MIP-2 have been identified in human, rat and cotton rat. MIP-2 is an ELR-containing member of the alpha (CXC) subfamily of chemokines. The cotton rat MIP-2 gene encodes a 101 amino acid (aa) residue precursor protein with a 28 aa putative signal peptide that is cleaved to generate the 73 aa mature protein. Mature cotton rat MIP-2 has two intrachain disulfide bonds and no potential glycosylation sites. It shares approximately 79 % and 85 % aa sequence identity with rat CINC-3 and mouse MIP-2, respectively. MIP-2 is a potent neutrophil attractant and activator. MIP-2 binds and activates the chemokine receptor CXCR-2. The recombinant cotton rat MIP-2 has been shown to bind and activate the human CXCR-2.
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Restrictions
- For Research Use only
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Stock
- 4 °C
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- CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))
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Autre désignation
- MIP-2
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Pathways
- Cellular Response to Molecule of Bacterial Origin
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