Interferon gamma Kit ELISA

N° du produit ABIN2690557

Kit ELISA Humain Interferon gamma, test Colorimetric pour la quantification de Humain Interferon gamma et a été mentionné dans 5+ publications.

Aperçu rapide pour Interferon gamma Kit ELISA (ABIN2690557)

Antigène: Interferon gamma (IFNG)

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Type d'échantillon: Serum, Plasma, Cell Culture Supernatant

Détail du produit Interferon gamma Kit ELISA

Seuil minimal de détection: 1.0 pg/mL

Fonction: The Human IFN-γ ELISA Kit II is for the in vitro quantitative determination of human IFN-γ in serum, plasma, and cell culture supernatant.

Marque: BD OptEIA™

Analytical Method: Quantitative

Information d'application

Indications d'application: The ELISA Kit II format was developed for superior accuracy with serum and plasma specimens. The data that demonstrates this enhancement can be located in the Performance "Recovery" and "Linearity" sections.

Commentaires:

BD OptEIA™ Human IFN-γ ELISA Kit II

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C

Stockage commentaire: 1. Store unopened kit at 2 - 8°C. Do not use kit after expiration date.
2. Before use, bring all reagents to room temperature (18 - 25°C). Immediately after use, return to proper storage conditions.
3. Lyophilized standards are stable until kit expiration date. After reconstitution, use freshly reconstituted standard within 12 hours (stored at 2 - 8°C).

Références pour Interferon gamma Kit ELISA (ABIN2690557)

Farrar, Schreiber: "The molecular cell biology of interferon-gamma and its receptor." dans: Annual review of immunology, Vol. 11, pp. 571-611, (1993) (PubMed).

Grossberg, Taylor, Kushnaryov: "Interferon receptors and their role in interferon action." dans: Experientia, Vol. 45, Issue 6, pp. 508-13, (1989) (PubMed).

Zoon: "Human interferons: structure and function." dans: Interferon, Vol. 9, pp. 1-12, (1988) (PubMed).

Rinderknecht, OConnor, Rodriguez: "Natural human interferon-gamma. Complete amino acid sequence and determination of sites of glycosylation." dans: The Journal of biological chemistry, Vol. 259, Issue 11, pp. 6790-7, (1984) (PubMed).

DeGrado, Wasserman, Chowdhry: "Sequence and structural homologies among type I and type II interferons." dans: Nature, Vol. 300, Issue 5890, pp. 379-81, (1983) (PubMed).

Détail du antigène

Antigène: Interferon gamma (IFNG)

Autre désignation: IFN-gamma

Sujet: Interferon-γ (IFN-γ) or immune interferon, is a potent multifunctional Type II interferon which is secreted by activated natural killer (NK) cells and T cells. IFN-γ binds to a different receptor than the Type I viral interferons IFN-α and IFN-β, with which little sequence homology is shared.
In addition to its antiviral effects, IFN-γ can upregulate a number of lymphoid cell functions, including the antimicrobial and antitumor responses of macrophages, NK cells, and neutrophils. In addition, IFN-γ can exert strong regulatory influences on the proliferation, differentiation, and effector responses of B cell and T cell subsets. These influences can involve IFN-γ's capacity to boost MHC class I and II expression by antigen-presenting cells as well as direct effects on B cells and T cells themselves. Human IFN-γ is a 35 kD protein containing 143 amino acid residues. This cytokine also upregulates ICAM-1 expression on endothelial cells, and has become a primary marker for Th1-like immune response research.

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy