Leptin Kit ELISA
Aperçu rapide pour Leptin Kit ELISA (ABIN5068384)
Antigène
Voir toutes Leptin (LEP) Kits ELISAReactivité
Méthode de détection
Application
Type d'échantillon
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Sensibilité
- 0.5 ng/mL
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Attributs du produit
- Leptin, Serum, Human, ELISA Kit (Ob, Obese Protein, Obesity Factor)
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Ingrédients
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- Microwell Strip Plate, 1x96wells
- Standard, 0ng/ml, 1x10ml
- Standard, 1ng/ml, 1x500ul
- Standard, 5ng/ml, 1x500ul
- Standard, 10ng/ml, 1x500ul
- Standard, 20ng/ml, 1x500ul
- Standard, 50ng/ml, 1x500ul
- Standard, 100ng/ml, 1x500ul
- Low Control, 1x500ul
- 0: High Control, 1x500ul
- 1: AB (Biotin), 1x10ml
- 2: Streptavidin (HRP) 50X, 1x400ul
- 3: Assay Buffer, 1x20ml
- 4: Wash Buffer, 10X, 1x50ml
- 5: TMB, 1x16ml
- 6: Stop Solution, 1x6ml
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Leptin (LEP) ELISA Kit
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Leptin (LEP) ELISA KitLEP Reactivité: Poulet Colorimetric Sandwich ELISA 31.2 pg/mL - 2000 pg/mL Plasma, Serum
Leptin (LEP) ELISA KitLEP Reactivité: Boeuf (Vache) Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Leptin (LEP) ELISA KitLEP Reactivité: Porc Colorimetric Sandwich ELISA 0.312 ng/mL - 20 ng/mL Plasma, Serum, Tissue Homogenate
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Restrictions
- For Research Use only
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Stock
- 4 °C
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Stockage commentaire
- 4°C
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- Leptin (LEP)
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Autre désignation
- Leptin
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Sujet
- Obesity, a common nutritional disorder, is associated with diabetes, hypertension, hyperlipidemia, cancer and many other health related problems. At least five genes, Obese (ob), diabetes (db), fat (fat), agouti yellow (Ay), and tubby (tub) have been linked to obesity. Recently, Ob genes (mouse and human) have been cloned. Obese gene encodes an adipocyte-tissue derived secreted Ob protein/Leptin (167aa, ~16kD) that controls body weight homeostasis. Exogenous administration of recombinant Ob protein can reduce food intake and body weight. However, Ob protein had no effect in db/db mice suggesting a defect in leptin signaling mechanism. Leptin exert its effects by interacting with leptin receptors (obese receptors). The Ob-R has been shown to be a product of db gene that has long been thought to encode the receptor for a weight-controlling hormone. The Ob-R has at least 6 alternatively spliced forms with modifications at the amino and C-terminus.
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Pathways
- Signalistation JAK/STAT, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
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