FLT4 Kit ELISA

N° du produit ABIN6719847

Détail du produit FLT4 Kit ELISA

Antigène: FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))

Reactivité: Souris

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 156 pg/mL - 10000 pg/mL

Seuil minimal de détection: 156 pg/mL

Application: ELISA

Fonction: Sandwich ELISA for Quantitative Detection of Antigen

Type d'échantillon: Cell Culture Supernatant, Serum

Analytical Method: Quantitative

Attributs du produit:

Synonyms: FLT 4, FLT4, FLT41, Fms like tyrosine kinase 4, Fms related tyrosine kinase 4, LMPH1A, PCL, Tyrosine protein kinase receptor FLT4, Vascular endothelial growth factor receptor 3, VEGFR 3, VEGFR3

Background: Fms-related tyrosine kinase 4, also known as FLT4 or VEGFR3, is a protein which in humans is encoded by the FLT4 gene. It is mapped to 5q35.3. This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. FLT4 has an essential role in the development of the embryonic cardiovascular system before the emergence of the lymphatic vessels. It has been found that FLT4, which provides proangiogenic signaling when expressed on endothelium, may also have antiangiogenic properties when expressed at an avascular site by nonendothelial cells. FLT4 is also regarded as a regulator of vascular network formation.

Gene Name: FLT4

Production: Natural and recombinant mouse VEGFR3. There is no detectable cross-reactivity with other relevant proteins.

Standard: Expression system for standard: NSO, Immunogen sequence: Y25-D770

Information d'application

Indications d'application:

Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 10000pg/mL, 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312pg/mL, 156pg/mL mouse VEGFR3 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of mouse cell culture supernates or serum to each empty well. It is recommended that each mouse VEGFR3 standard solution and each sample be measured in duplicate.

ELISA Dilution: 156pg/mL-10000pg/mL

Volume d'échantillon: 100 μL

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: RT,4 °C,-20 °C

Stockage commentaire: Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.

Détail du antigène

Antigène: FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))

Autre désignation: VEGFR3 - FLT4 (FLT4 Produits)

Synonymes: FLT41 Kit ELISA, LMPH1A Kit ELISA, PCL Kit ELISA, VEGFR3 Kit ELISA, AI323512 Kit ELISA, Chy Kit ELISA, Flt-4 Kit ELISA, VEGFR-3 Kit ELISA, Vegfr3 Kit ELISA, cb1059 Kit ELISA, fms related tyrosine kinase 4 Kit ELISA, FMS-like tyrosine kinase 4 Kit ELISA, fms-related tyrosine kinase 4 Kit ELISA, FLT4 Kit ELISA, Flt4 Kit ELISA, flt4 Kit ELISA

ID gène: 14257

NCBI Accession: NP_032055

UniProt: P35917

Pathways: Signalisation RTK, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling