KPNA2 Produits
(Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))
Catégories
The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination [provided by RefSeq, Jul 2008].
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Catégories KPNA2 en vedette
KPNA2 Anticorps
High quality antibodies with extensive validation data.
KPNA2 Kits ELISA
Reliable ELISA kits for a wide range of species.
KPNA2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
KPNA2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, ICC, FACS
Validations
- (8)
N° du produit
ABIN5542626
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
N° du produit
ABIN7156118
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, ICC, IHC (p)
Validations
- (1)
- (3)
N° du produit
ABIN2856324
Quantité
100 μL
Fiche technique
Fiche technique
KPNA2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
N° du produit
ABIN6957267
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968099
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4883449
Quantité
96 tests
Fiche technique
Fiche technique
KPNA2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1308916
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1308918
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123665
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits KPNA2
: "Association of overexpressed karyopherin alpha 2 with poor survival and its contribution to interleukin-1β-induced matrix metalloproteinase expression in oral cancer." dans: Head & neck, Vol. 40, Issue 8, pp. 1719-1733, (2018) (PubMed).: "KPNA2 is a potential diagnostic serum biomarker for epithelial ovarian cancer and correlates with poor prognosis." dans: Tumour biology, Vol. 39, Issue 6, pp. 1010428317706289, (2017) (PubMed).
: "Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-κB." dans: Journal of virology, Vol. 91, Issue 8, (2017) (PubMed).
: "Essential elements for translation: the germline factor Vasa functions broadly in somatic cells." dans: Development (Cambridge, England), Vol. 142, Issue 11, pp. 1960-70, (2015) (PubMed).
: "Akt-mediated phosphorylation increases the binding affinity of hTERT for importin α to promote nuclear translocation." dans: Journal of cell science, Vol. 128, Issue 12, pp. 2287-301, (2015) (PubMed).
: "KPNA2 is a promising biomarker candidate for esophageal squamous cell carcinoma and correlates with cell proliferation." dans: Oncology reports, Vol. 32, Issue 4, pp. 1631-7, (2014) (PubMed).
: "Tyrosine 132 phosphorylation of influenza A virus M1 protein is crucial for virus replication by controlling the nuclear import of M1." dans: Journal of virology, Vol. 87, Issue 11, pp. 6182-91, (2013) (PubMed).
: "Importin subunit alpha-2 is identified as a potential biomarker for non-small cell lung cancer by integration of the cancer cell secretome and tissue transcriptome." dans: International journal of cancer. Journal international du cancer, Vol. 128, Issue 10, pp. 2364-72, (2011) (PubMed).
: "Facioscapulohumeral muscular dystrophy region gene 1 is a dynamic RNA-associated and actin-bundling protein." dans: Journal of molecular biology, Vol. 411, Issue 2, pp. 397-416, (2011) (PubMed).
: "Cutting edge: tubulin ? functions as an adaptor in NFAT-importin ? interaction." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 5, pp. 2710-3, (2011) (PubMed).
Synonymes et noms alternatifs relatifs à KPNA2
karyopherin subunit alpha 2 (KPNA2), importin subunit alpha-2 (EDI_246290), importin subunit alpha-2 (EDI_335040), Importin subunit alpha-2 (ima2), karyopherin subunit alpha 2 (Kpna2), karyopherin (importin) alpha 2 (Kpna2), karyopherin alpha-2 subunit like L homeolog (kpna2.L), karyopherin alpha 2 (RAG cohort 1, importin alpha 1) (kpna2), 2410044B12Rik, hm:zeh0389, hm:zeh0389r, ima2, importin, IPOA1, ipoa1, kpna2, PTAC58, QIP2, qip2, RCH1, Rch1, rch1, SRP1alpha, srp1alpha, zgc:86945, zgc:113902Protein level used designations for KPNA2
- RAG cohort 1
- RAG cohort protein 1
- SRP1-alpha
- importin alpha 1
- importin alpha 2
- importin subunit alpha-1
- importin subunit alpha-2
- importin-alpha-P1
- karyopherin subunit alpha-2
- pendulin
- Importin subunit alpha-2
- karyopherin (importin) alpha 2
- nuclear import protein
- importin alpha P1
- m-importin-alpha-P1
- pore targeting complex 58 kDa subunit
- karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
- karyopherin alpha-2 subunit like L homeolog
- zeh0389
- zeh0389r
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