KPNB1 Produits
(Karyopherin (Importin) beta 1 (KPNB1))
Catégories
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013].
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Catégories KPNB1 en vedette
KPNB1 Anticorps
High quality antibodies with extensive validation data.
KPNB1 Kits ELISA
Reliable ELISA kits for a wide range of species.
KPNB1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
KPNB1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
N° du produit
ABIN6142997
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Rat
Application
WB, ELISA, IHC, FACS, IF
Validations
- (5)
N° du produit
ABIN185516
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (3)
N° du produit
ABIN390792
Quantité
400 μL
Fiche technique
Fiche technique
KPNB1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6957266
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5656173
Quantité
96 tests
Fiche technique
Fiche technique
KPNB1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1308928
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3093074
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3134614
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits KPNB1
: "Antiviral activity of a purine synthesis enzyme reveals a key role of deamidation in regulating protein nuclear import." dans: Science advances, Vol. 5, Issue 10, pp. eaaw7373, (2019) (PubMed).: "Osteoblast regulation via ligand-activated nuclear trafficking of the oxytocin receptor." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 46, pp. 16502-7, (2014) (PubMed).
: "Multiple importins function as nuclear transport receptors for the Rev protein of human immunodeficiency virus type 1." dans: The Journal of biological chemistry, Vol. 281, Issue 30, pp. 20883-90, (2006) (PubMed).
: "Spatial coordination of spindle assembly by chromosome-mediated signaling gradients." dans: Science (New York, N.Y.), Vol. 309, Issue 5739, pp. 1373-6, (2005) (PubMed).
: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." dans: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, (2002) (PubMed).
: "Exercise training attenuates coronary smooth muscle phenotypic modulation and nuclear Ca2+ signaling." dans: American journal of physiology. Heart and circulatory physiology, Vol. 283, Issue 6, pp. H2397-410, (2002) (PubMed).
: "Role of importin-beta in coupling Ran to downstream targets in microtubule assembly." dans: Science (New York, N.Y.), Vol. 291, Issue 5504, pp. 653-6, (2001) (PubMed).
: "The path of RNA through nuclear pores: apparent entry from the sides into specialized pores." dans: Journal of cell science, Vol. 113 Pt 2, pp. 291-302, (2000) (PubMed).
: "Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins." dans: Cell, Vol. 83, Issue 5, pp. 683-92, (1996) (PubMed).
: "Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 5, pp. 1769-73, (1995) (PubMed).
Synonymes et noms alternatifs relatifs à KPNB1
importin beta-1 subunit (AFUA_1G15720), importin beta-1 subunit (AOR_1_1974174), Importin beta-1 subunit (Bm1_57540), importin beta-1 subunit (PMAA_065830), importin beta-1 subunit (AFLA_083750), importin beta-1 subunit (TSTA_085870), importin beta-1 subunit (BDBG_07509), importin beta-1 subunit (MCYG_00039), karyopherin (importin) beta 1 L homeolog (kpnb1.L), importin beta 1 (LOC100533387), karyopherin subunit beta 1 (KPNB1), karyopherin (importin) beta 1 (Kpnb1), karyopherin subunit beta 1 (Kpnb1), AA409963, Afu1g15720, AO090005001133, imb1, IMB1, impnb, Impnb, ipo1, IPO1, ipob, IPOB, ntf97, NTF97Protein level used designations for KPNB1
- Importin beta-1 subunit
- importin beta-1 subunit
- importin beta 1
- PTAC97
- importin 1
- importin 90
- importin subunit beta-1
- importin-90
- karyopherin subunit beta-1
- nuclear factor p97
- pore targeting complex 97 kDa subunit
- SCG
- importin beta
- Importin beta
- karyopherin,beta 1
- nuclear factor P97
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