LEF1 Produits
(Lymphoid Enhancer-Binding Factor 1 (LEF1))
Catégories
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
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Catégories LEF1 en vedette
LEF1 Anticorps
High quality antibodies with extensive validation data.
LEF1 Kits ELISA
Reliable ELISA kits for a wide range of species.
LEF1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
LEF1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB
Validations
- (1)
- (6)
- (1)
N° du produit
ABIN5663810
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (3)
- (6)
N° du produit
ABIN735248
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (2)
- (6)
N° du produit
ABIN565556
Quantité
100 μg
Fiche technique
Fiche technique
LEF1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6219167
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6219163
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6219160
Quantité
96 tests
Fiche technique
Fiche technique
LEF1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1309292
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123803
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1309294
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits LEF1
: "38" dans: , Vol. 1363, Issue Nucleic acids research, pp. 28-39, (1991): "A new cut&run low volume-urea (LoV-U) protocol optimized for transcriptional co-factors uncovers Wnt/b-catenin tissue-specific genomic targets." dans: Development (Cambridge, England), (2022) (PubMed).
: "Proteome Profile and Quantitative Proteomic Analysis of Buffalo (Bubalusbubalis) Follicular Fluid during Follicle Development." dans: International journal of molecular sciences, Vol. 17, Issue 5, (2016) (PubMed).
: "Resveratrol Attenuates Hyperoxia-induced Oxidative Stress, Inflammation and Fibrosis and Suppresses Wnt/?-catenin Signaling in Lungs of Neonatal Rats." dans: Clinical and experimental pharmacology & physiology, (2015) (PubMed).
: "MiR-27a regulates Wnt/beta-catenin signaling through targeting SFRP1 in glioma." dans: Neuroreport, Vol. 26, Issue 12, pp. 695-702, (2015) (PubMed).
: "Methylprednisolone suppresses the Wnt signaling pathway in chronic lymphocytic leukemia cell line MEC-1 regulated by LEF-1 expression." dans: International journal of clinical and experimental pathology, Vol. 8, Issue 7, pp. 7921-8, (2015) (PubMed).
: "The Regenerating Spinal Cord of Gecko Maintains Unaltered Expression of ?-Catenin Following Tail Amputation." dans: Journal of molecular neuroscience : MN, (2014) (PubMed).
: "Identification of DNA-dependent protein kinase catalytic subunit as a novel interaction partner of lymphocyte enhancer factor 1." dans: Medical molecular morphology, Vol. 46, Issue 1, pp. 14-9, (2013) (PubMed).
: "Regulation of ?-catenin nuclear dynamics by GSK-3? involves a LEF-1 positive feedback loop." dans: Traffic (Copenhagen, Denmark), Vol. 12, Issue 8, pp. 983-99, (2011) (PubMed).
: "LEF-1 is a prosurvival factor in chronic lymphocytic leukemia and is expressed in the preleukemic state of monoclonal B-cell lymphocytosis." dans: Blood, Vol. 116, Issue 16, pp. 2975-83, (2010) (PubMed).
Synonymes et noms alternatifs relatifs à LEF1
lymphoid enhancer binding factor 1 (LEF1), lymphoid enhancer binding factor 1 (lef1), lymphoid enhancer-binding factor 1 (lef1), lymphoid enhancer binding factor 1 (Lef1), lymphoid enhancer factor XLEF-1B (lef1), 3000002B05, AI451430, Lef-1, LEF-1, LEF1, TCF1ALPHA, TCF7L3, TCF10Protein level used designations for LEF1
- lymphoid enhancer binding factor-1
- lymphoid enhancer-binding factor 1
- lymphoid enhancer-binding factor 1-like
- etID310027.1
- LEF-1
- lymphoid enhancer binding factor 1 short isoform
- T cell-specific transcription factor 1-alpha
- TCF1-alpha
- lymphiod enhancer binding factor 1
- transcription factor LEF-1
- lymphoid enhancer binding factor 1
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