Left-Right Determination Factor Produits
(Left-Right Determination Factor (LEFTY-A))
Catégories
This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2010].
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Catégories Left-Right Determination Factor en vedette
Left-Right Determination Factor Anticorps
High quality antibodies with extensive validation data.
Left-Right Determination Factor recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Application
WB, ELISA, IHC, IP, RIA
Validations
- (3)
- (1)
N° du produit
ABIN103459
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
N° du produit
ABIN1983337
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
N° du produit
ABIN1886266
Quantité
100 μL
Fiche technique
Fiche technique
Left-Right Determination Factor recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4883592
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6386359
Quantité
96 tests
Fiche technique
Fiche technique
Dernières publications sur nos produits Left-Right Determination Factor
: "Lefty inhibits receptor-regulated Smad phosphorylation induced by the activated transforming growth factor-beta receptor." dans: The Journal of biological chemistry, Vol. 276, Issue 24, pp. 21397-404, (2001) (PubMed).: "Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 20, pp. 11376-81, (1999) (PubMed).
: "lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal." dans: Cell, Vol. 94, Issue 3, pp. 287-97, (1998) (PubMed).
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