LGMN Protéines
(Legumain (LGMN))
This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq, Jul 2008].
| Catalog no. | Produit | Reactivité | Hôte / Clonalité | Application | Prix et délai de livraison |
|---|---|---|---|---|---|
| LGMN Protein (AA 18-325) (His tag) | Souris | Levure |
|
636,17 €
Voir le prix
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|
| LGMN Protein (AA 18-323) (His tag) | Orang-Utan | Levure |
|
2.816,00 €
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|
|
| LGMN Protein (AA 19-432) (His tag) | Humain | Bacteria |
|
302,50 €
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|
|
| LGMN Protéine | Humain | Leishmania tarentolae |
|
1.354,65 €
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|
|
| LGMN Protein (His tag) | Humain | Escherichia coli (E. coli) |
|
503,00 €
Voir le prix
|
|
| LGMN Protein (His tag) | Souris | Mammalian Cells |
|
730,00 €
Voir le prix
|
|
| LGMN Protein (His tag) | Souris | Escherichia coli (E. coli) |
|
690,80 €
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|
|
| LGMN Protein (His tag) | Humain | Escherichia coli (E. coli) |
|
515,90 €
Voir le prix
|
|
| LGMN Protein (His tag) | Souris | Human Cells |
|
878,90 €
Voir le prix
|
|
| LGMN Protein (His tag) | Humain | Human Cells |
|
878,90 €
Voir le prix
|
|
| LGMN Protein (His tag) | Souris | Levure |
|
818,40 €
Voir le prix
|
|
| LGMN Protein (His tag) | Humain | Levure |
|
688,60 €
Voir le prix
|
|
| LGMN Protéine | Humain | Leishmania tarentolae |
|
338,80 €
Voir le prix
|
Protein
- ELISA (ELISA: Application indiquée)
- Origine
- Souris
- Hôte
- Levure
- Type Proteine
- Recombinant
- Pureté
- > 90 %
Protein
- ELISA (ELISA: Application indiquée)
- Origine
- Orang-Utan
- Hôte
- Levure
- Type Proteine
- Recombinant
- Pureté
- > 90 %
Protein
- Origine
- Humain
- Hôte
- Leishmania tarentolae
- Type Proteine
- Recombinant
- Pureté
- > 90 % (SDS-PAGE)
Protein
- SDS (SDS-PAGE: Application indiquée)
- WB (Western Blotting: Application indiquée)
- ELISA (ELISA: Application indiquée)
- Imm (Immunogen: Application indiquée)
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
Protein
- SDS (SDS-PAGE: Application indiquée)
- WB (Western Blotting: Application indiquée)
- ELISA (ELISA: Application indiquée)
- Imm (Immunogen: Application indiquée)
- Origine
- Souris
- Hôte
- Mammalian Cells
- Type Proteine
- Recombinant
Protein
- Origine
- Souris
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- Greater than 90 % as determined by SDS-PAGE.
Protein
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- Greater than 90 % as determined by SDS-PAGE.
Protein
- Origine
- Souris
- Hôte
- Human Cells
- Type Proteine
- Recombinant
- Pureté
- Greater than 95 % as determined by reducing SDS-PAGE.
Protein
- Origine
- Humain
- Hôte
- Human Cells
- Type Proteine
- Recombinant
- Pureté
- Greater than 95 % as determined by reducing SDS-PAGE.
Protein
- Origine
- Souris
- Hôte
- Levure
- Type Proteine
- Recombinant
- Pureté
- Greater than 90 % as determined by SDS-PAGE.
Protein
- Origine
- Humain
- Hôte
- Levure
- Type Proteine
- Recombinant
- Pureté
- Greater than 90 % as determined by SDS-PAGE.
Protein
- Origine
- Humain
- Hôte
- Leishmania tarentolae
- Type Proteine
- Recombinant
- Pureté
- > 90 % (SDS-PAGE)
Dernières publications pour nos LGMN Protéines
: "Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage." dans: Cell research, Vol. 24, Issue 3, pp. 344-58, (2014) (PubMed).
: "Legumain protease-activated TAT-liposome cargo for targeting tumours and their microenvironment." dans: Nature communications, Vol. 5, pp. 4280, (2014) (PubMed).
: "Degradation of acetoacetyl-CoA synthetase, a ketone body-utilizing enzyme, by legumain in the mouse kidney." dans: Biochemical and biophysical research communications, Vol. 453, Issue 3, pp. 631-5, (2014) (PubMed).
: "Legumain protease-activated TAT-liposome cargo for targeting tumours and their microenvironment." dans: Nature communications, Vol. 5, pp. 4280, (2014) (PubMed).
: "Degradation of acetoacetyl-CoA synthetase, a ketone body-utilizing enzyme, by legumain in the mouse kidney." dans: Biochemical and biophysical research communications, Vol. 453, Issue 3, pp. 631-5, (2014) (PubMed).
Pseudonymes pour LGMN Protéines
legumain (LGMN) Protéineslegumain (Lgmn) Protéines
legumain L homeolog (lgmn.L) Protéines
legumain (lgmn) Protéines
delta vacuolar processing enzyme (DELTA-VPE) Protéines
legumain (MBOO_RS07785) Protéines
Legumain (Odosp_3582) Protéines
legumain (LOC569153) Protéines
AEP Protéines
AI746452 Protéines
AU022324 Protéines
cb173 Protéines
cb460 Protéines
DELTA VACUOLAR PROCESSING ENZYME Protéines
delta vacuolar processing enzyme Protéines
DELTAVPE Protéines
lgmn Protéines
LGMN1 Protéines
MGC64351 Protéines
MGC88980 Protéines
PRSC1 Protéines
Prsc1 Protéines
sb:cb173 Protéines
wu:fa98g05 Protéines
wu:fj92g08 Protéines
zgc:76953 Protéines
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