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MACC1 Produits

(Metastasis Associated in Colon Cancer 1 (MACC1))
MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM, Mar 2009].

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Catégories MACC1 en vedette

MACC1 Anticorps

High quality antibodies with extensive validation data.

MACC1 Kits ELISA

Reliable ELISA kits for a wide range of species.

MACC1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MACC1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (6)
  • (5)
N° du produit ABIN706526
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7159558
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application IHC (p), IF
Validations
  • (2)
N° du produit ABIN5650059
Quantité 100 μL
Fiche technique Fiche technique

MACC1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6957784
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6975740
Quantité 96 tests
Fiche technique Fiche technique

MACC1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3093653
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7386299
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3010685
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MACC1

Shi, Song, Wang, Zhang, Zheng: "MACC‑1 antibody target therapy suppresses growth and migration of non‑small cell lung cancer." dans: Molecular medicine reports, Vol. 16, Issue 5, pp. 7329-7336, (2017) (PubMed).

Montorsi, Guizzetti, Alecci, Caporali, Martello, Atene, Parenti, Pizzini, Zanovello, Bortoluzzi, Ferrari, Grande, Zanocco-Marani: "Loss of zfp36 expression in colorectal cancer correlates to wnt/ ß-catenin activity and enhances epithelial-to-mesenchymal transition through upregulation of zeb1, sox9 and macc1." dans: Oncotarget, Vol. 7, Issue 37, pp. 59144-59157, (2016) (PubMed).

Liu, Pan, Guo, Wu, Guo, Peng, Wu, Zuo: "A new mechanism of trastuzumab resistance in gastric cancer: MACC1 promotes the Warburg effect via activation of the PI3K/AKT signaling pathway." dans: Journal of hematology & oncology, Vol. 9, Issue 1, pp. 76, (2016) (PubMed).

Sun, Li, Dai, Tan, Zhao, Li, Wang: "Silence of MACC1 expression by RNA interference inhibits proliferation, invasion and metastasis, and promotes apoptosis in U251 human malignant glioma cells." dans: Molecular medicine reports, Vol. 12, Issue 3, pp. 3423-31, (2015) (PubMed).

Ge, Meng, Zhou, Zhang, Ding: "Positive MACC1 expression correlates with invasive behaviors and postoperative liver metastasis in colon cancer." dans: International journal of clinical and experimental medicine, Vol. 8, Issue 1, pp. 1094-100, (2015) (PubMed).

Koelzer, Herrmann, Zlobec, Karamitopoulou, Lugli, Stein: "Heterogeneity analysis of Metastasis Associated in Colon Cancer 1 (MACC1) for survival prognosis of colorectal cancer patients: a retrospective cohort study." dans: BMC cancer, Vol. 15, pp. 160, (2015) (PubMed).

Li, Zhang, Zhao, Shi, Yao, Zhang, Guo, Liu: "Overexpression of MACC1 and the association with hepatocyte growth factor/c-Met in epithelial ovarian cancer." dans: Oncology letters, Vol. 9, Issue 5, pp. 1989-1996, (2015) (PubMed).

Kuo, Wu, Chang, Huang, Lin, Yan, Sheu, Lu, Chang, Lai, Wang: "Low SOX17 expression is a prognostic factor and drives transcriptional dysregulation and esophageal cancer progression." dans: International journal of cancer, Vol. 135, Issue 3, pp. 563-73, (2014) (PubMed).

Hagemann, Fuchs, Monoranu, Herrmann, Smith, Hohmann, Grabiec, Kessler, Dehghani, Löhr, Ernestus, Vince, Stein: "Impact of MACC1 on human malignant glioma progression and patients' unfavorable prognosis." dans: Neuro-oncology, Vol. 15, Issue 12, pp. 1696-709, (2013) (PubMed).

Guo, Yang, Yao, Zhang, Da, Duan: "Expression of MACC1 and c-Met in human gastric cancer and its clinical significance." dans: Cancer cell international, Vol. 13, Issue 1, pp. 121, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à MACC1

MACC1, MET transcriptional regulator (MACC1), metastasis associated in colon cancer 1 (Macc1), MACC1, MET transcriptional regulator (Macc1), 7A5, 7a5, 4732474O15Rik, Gm267, RGD1309838, SH3BP4L

Protein level used designations for MACC1

  • SH3 domain-containing protein 7a5
  • metastasis-associated in colon cancer protein 1
  • putative binding protein 7a5
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