MADD Produits
(MAP-Kinase Activating Death Domain (MADD))
Catégories
Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
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Catégories MADD en vedette
MADD Anticorps
High quality antibodies with extensive validation data.
MADD Kits ELISA
Reliable ELISA kits for a wide range of species.
MADD recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (2)
N° du produit
ABIN7187234
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF
Validations
- (2)
N° du produit
ABIN3185435
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (fro)
Validations
- (1)
- (1)
N° du produit
ABIN2475471
Quantité
0.1 mg
Fiche technique
Fiche technique
MADD recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN5648202
Quantité
96 tests
Fiche technique
Fiche technique
MADD recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3093738
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3136009
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7422859
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits MADD
: "Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors." dans: The Journal of cell biology, Vol. 191, Issue 2, pp. 367-81, (2010) (PubMed).: "GFRalpha-2 and GFRalpha-3 are two new receptors for ligands of the GDNF family." dans: The Journal of biological chemistry, Vol. 272, Issue 52, pp. 33111-7, (1998) (PubMed).
: "Persephin, a novel neurotrophic factor related to GDNF and neurturin. ..." dans: Neuron, Vol. 20, Issue 2, pp. 245-53, (1998) (PubMed).
: "GFRalpha3 is an orphan member of the GDNF/neurturin/persephin receptor family." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 10, pp. 5801-6, (1998) (PubMed).
Synonymes et noms alternatifs relatifs à MADD
MAP kinase activating death domain (MADD), MAP-kinase activating death domain (madd), MAP kinase activating death domain (madd), MAP-kinase activating death domain (Madd), 9630059K23Rik, DENN, IG20, MADD, MGC145371, RAB3GEPProtein level used designations for MADD
- MAP-kinase activating death domain
- MAP kinase-activating death domain protein
- MAP kinase-activating death domain protein-like
- Rab3 GDP/GTP exchange factor
- differentially expressed in normal and neoplastic cells
- insulinoma glucagonoma clone 20
- Rab3 GDP/GTP exchange protein
- Rab3 GEP
- insulinoma-glucagonoma protein 20
- rab3 GDP/GTP exchange factor
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