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Major Basic Protein Produits

(Major Basic Protein)

Catégories

The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called 'Golli-MBP') that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq, Jul 2008].

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Catégories Major Basic Protein en vedette

Major Basic Protein Anticorps

High quality antibodies with extensive validation data.

Major Basic Protein Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Major Basic Protein recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (4)
N° du produit ABIN7428050
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
N° du produit ABIN7429931
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
N° du produit ABIN7426883
Quantité 100 μL
Fiche technique Fiche technique

Major Basic Protein recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (5)
N° du produit ABIN6720571
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957619
Quantité 96 tests
Fiche technique Fiche technique

Major Basic Protein recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Pig
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7394501
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7394495
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7405675
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Major Basic Protein

Sakai-Kashiwabara, Asano: "Inhibitory action of quercetin on eosinophil activation in vitro." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2013, pp. 127105, (2013) (PubMed).

Kingsnorth: "Ornithine decarboxylase as a marker for colorectal adenomas." dans: The British journal of surgery, Vol. 74, Issue 11, pp. 1066, (1988) (PubMed).

Synonymes et noms alternatifs relatifs à Major Basic Protein

myelin basic protein (MBP), proteoglycan 2, bone marrow (Prg2), MBP, mMBP, mMBP-1

Protein level used designations for Major Basic Protein

  • myelin A1 protein
  • myelin membrane encephalitogenic protein
  • BMPG
  • bone marrow proteoglycan
  • major basic protein 1
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