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MAK Produits

(Male Germ Cell-Associated Kinase (MAK))

Catégories

The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011].

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Catégories MAK en vedette

MAK Anticorps

High quality antibodies with extensive validation data.

MAK Kits ELISA

Reliable ELISA kits for a wide range of species.

MAK Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MAK recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (6)
N° du produit ABIN517720
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
  • (3)
N° du produit ABIN391782
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (4)
N° du produit ABIN7268382
Quantité 100 μL
Fiche technique Fiche technique

MAK recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1381289
Quantité 96 tests
Fiche technique Fiche technique

MAK recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310104
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310103
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3093753
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits MAK

Li, Rao, Zheng-Le, Hurd, Lillo, Khanna: "Loss of retinitis pigmentosa 2 (RP2) protein affects cone photoreceptor sensory cilium elongation in mice." dans: Cytoskeleton (Hoboken, N.J.), (2015) (PubMed).

Tucker, Scheetz, Mullins, DeLuca, Hoffmann, Johnston, Jacobson, Sheffield, Stone: "Exome sequencing and analysis of induced pluripotent stem cells identify the cilia-related gene male germ cell-associated kinase (MAK) as a cause of retinitis pigmentosa." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 34, pp. E569-76, (2011) (PubMed).

Ma, Xia, Desai, Boucher, Guan, Shih, Shi, deVere White, Chen, Tepper, Kung: "Male germ cell-associated kinase, a male-specific kinase regulated by androgen, is a coactivator of androgen receptor in prostate cancer cells." dans: Cancer research, Vol. 66, Issue 17, pp. 8439-47, (2006) (PubMed).

Fu, Larson, Chitta, Parker, Turk, Lawrence, Kaldis, Galaktionov, Cohn, Shabanowitz, Hunt, Sturgill: "Identification of yin-yang regulators and a phosphorylation consensus for male germ cell-associated kinase (MAK)-related kinase." dans: Molecular and cellular biology, Vol. 26, Issue 22, pp. 8639-54, (2006) (PubMed).

Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: "The DNA sequence and analysis of human chromosome 6. ..." dans: Nature, Vol. 425, Issue 6960, pp. 805-11, (2003) (PubMed).

Xia, Robinson, Ma, Chen, Wu, Qiu, Kung: "Identification of human male germ cell-associated kinase, a kinase transcriptionally activated by androgen in prostate cancer cells." dans: The Journal of biological chemistry, Vol. 277, Issue 38, pp. 35422-33, (2002) (PubMed).

Woodle, Newman, Cohen: "Sterically stabilized liposomes: physical and biological properties." dans: Journal of drug targeting, Vol. 2, Issue 5, pp. 397-403, (1995) (PubMed).

Synonymes et noms alternatifs relatifs à MAK

male germ cell associated kinase (MAK), male germ cell-associated kinase (Mak), male germ cell-associated kinase (mak), male germ cell associated kinase L homeolog (mak.L), male germ cell associated kinase (mak), A930010O05Rik, dJ417M14.2, fj04c02, Ick, MGC82717, MGC146434, RP62, rp62, wu:fj04c02, xmak, zgc:56603

Protein level used designations for MAK

  • male germ cell-associated kinase retinal-enriched isoform
  • serine/threonine protein kinase MAK
  • serine/threonine-protein kinase MAK
  • protein kinase RCK
  • intestinal cell kinase
  • male germ cell-associated kinase
  • serine/threonine-protein kinase MAK-like
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