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MARCO Produits

(Macrophage Receptor with Collagenous Structure (MARCO))
The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq, Jul 2008].

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Catégories MARCO en vedette

MARCO Anticorps

High quality antibodies with extensive validation data.

MARCO Kits ELISA

Reliable ELISA kits for a wide range of species.

MARCO Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MARCO recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (4)
N° du produit ABIN7444610
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (2)
  • (3)
N° du produit ABIN653847
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
N° du produit ABIN7158886
Quantité 100 μL
Fiche technique Fiche technique

MARCO recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6730744
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1141381
Quantité 96 tests
Fiche technique Fiche technique

MARCO recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275279
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275278
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3083564
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits MARCO

Wu, Dayanand, Thylur, Norbury, Gowda: "Small molecule-based inhibition of MEK1/2 proteins dampens inflammatory responses to malaria, reduces parasite load, and mitigates pathogenic outcomes." dans: The Journal of biological chemistry, Vol. 292, Issue 33, pp. 13615-13634, (2017) (PubMed).

Ohta, Moriyama, Maehara, Gion, Furukawa, Tanaka, Hayashida, Yamauchi, Ishiguro, Mikami, Tsuboi, Iizuka-Koga, Kawano, Sato, Kiyoshima, Sumida, Nakamura: "DNA Microarray Analysis of Submandibular Glands in IgG4-Related Disease Indicates a Role for MARCO and Other Innate Immune-Related Proteins." dans: Medicine, Vol. 95, Issue 7, pp. e2853, (2016) (PubMed).

Wu, Gowda, Gowda et al.: "Phagosomal Acidification Prevents Macrophage Inflammatory Cytokine Production to Malaria, and Dendritic Cells Are the Major Source at the Early Stages of Infection: IMPLICATION FOR MALARIA PROTECTIVE ..." dans: The Journal of biological chemistry, Vol. 290, Issue 38, pp. 23135-47, (2015) (PubMed).

Kanayama, He, Shinohara: "The lung is protected from spontaneous inflammation by autophagy in myeloid cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 11, pp. 5465-71, (2015) (PubMed).

Chao, Makale, Karmali, Sharikov, Tsigelny, Merkulov, Kesari, Wrasidlo, Ruoslahti, Simberg: "Recognition of dextran-superparamagnetic iron oxide nanoparticle conjugates (Feridex) via macrophage scavenger receptor charged domains." dans: Bioconjugate chemistry, Vol. 23, Issue 5, pp. 1003-9, (2014) (PubMed).

Tighe, Li, Potts, Frush, Liu, Gunn, Foster, Noble, Hollingsworth: "Ozone inhalation promotes CX3CR1-dependent maturation of resident lung macrophages that limit oxidative stress and inflammation." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 9, pp. 4800-8, (2011) (PubMed).

Arredouani, Palecanda, Koziel, Huang, Imrich, Sulahian, Ning, Yang, Pikkarainen, Sankala, Vargas, Takeya, Tryggvason, Kobzik: "MARCO is the major binding receptor for unopsonized particles and bacteria on human alveolar macrophages." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 9, pp. 6058-64, (2005) (PubMed).

Bunn, Kobzik, Grigg: "MARCO expression on pediatric alveolar macrophages." dans: Cytometry. Part B, Clinical cytometry, Vol. 60, Issue 1, pp. 54-6, (2004) (PubMed).

Grolleau, Misek, Kuick, Hanash, Mulé: "Inducible expression of macrophage receptor Marco by dendritic cells following phagocytic uptake of dead cells uncovered by oligonucleotide arrays." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 6, pp. 2879-88, (2003) (PubMed).

Palecanda, Kobzik: "Receptors for unopsonized particles: the role of alveolar macrophage scavenger receptors." dans: Current molecular medicine, Vol. 1, Issue 5, pp. 589-95, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à MARCO

macrophage receptor with collagenous structure (MARCO), macrophage receptor with collagenous structure (Marco), AI323439, Ly112, Scara2, SCARA2

Protein level used designations for MARCO

  • macrophage receptor MARCO
  • scavenger receptor class A member 2
  • scavenger receptor class A, member 2
  • putative scavenger receptor MARCO
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