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MAPKAP Kinase 5 Produits

(Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))

Catégories

The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012].

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Catégories MAPKAP Kinase 5 en vedette

MAPKAP Kinase 5 Anticorps

High quality antibodies with extensive validation data.

MAPKAP Kinase 5 Kits ELISA

Reliable ELISA kits for a wide range of species.

MAPKAP Kinase 5 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MAPKAP Kinase 5 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (3)
N° du produit ABIN710546
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (1)
  • (2)
N° du produit ABIN389587
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
  • (2)
N° du produit ABIN969362
Quantité 100 μL
Fiche technique Fiche technique

MAPKAP Kinase 5 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380844
Quantité 2 x 96 tests
Fiche technique Fiche technique

MAPKAP Kinase 5 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (2)
N° du produit ABIN1310330
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310332
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
N° du produit ABIN7317049
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MAPKAP Kinase 5

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." dans: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Daily, Monks, Leggas, Moscow: "Abrogation of microcystin cytotoxicity by MAP kinase inhibitors and N-acetyl cysteine is confounded by OATPIB1 uptake activity inhibition." dans: Toxicon : official journal of the International Society on Toxinology, Vol. 55, Issue 4, pp. 827-37, (2010) (PubMed).

Marasa, Srikantan, Masuda, Abdelmohsen, Kuwano, Yang, Martindale, Rinker-Schaeffer, Gorospe: "Increased MKK4 abundance with replicative senescence is linked to the joint reduction of multiple microRNAs." dans: Science signaling, Vol. 2, Issue 94, pp. ra69, (2009) (PubMed).

Sun, Yoshizuka, New, Moser, Li, Liao, Xie, Chen, Deng, Yamout, Dong, Frangou, Yates, Wright, Han: "PRAK is essential for ras-induced senescence and tumor suppression." dans: Cell, Vol. 128, Issue 2, pp. 295-308, (2007) (PubMed).

Paliga, Natale, Watson: "p38 mitogen-activated protein kinase (MAPK) first regulates filamentous actin at the 8-16-cell stage during preimplantation development." dans: Biology of the cell / under the auspices of the European Cell Biology Organization, Vol. 97, Issue 8, pp. 629-40, (2005) (PubMed).

Wijtten, Prak, Lemme, Langhout: "Effect of different dietary ideal protein concentrations on broiler performance." dans: British poultry science, Vol. 45, Issue 4, pp. 504-11, (2004) (PubMed).

New, Jiang, Han: "Regulation of PRAK subcellular location by p38 MAP kinases." dans: Molecular biology of the cell, Vol. 14, Issue 6, pp. 2603-16, (2003) (PubMed).

Sudo, Maruyama, Osada: "p62 functions as a p38 MAP kinase regulator." dans: Biochemical and biophysical research communications, Vol. 269, Issue 2, pp. 521-5, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à MAPKAP Kinase 5

mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), mitogen-activated protein kinase-activated protein kinase 5 (mapkapk5), MAP kinase-activated protein kinase 5 (Mapkapk5), mitogen-activated protein kinase-activated protein kinase 5 (Mapkapk5), MAPKAP-K5, MAPKAPK5, MK-5, MK5, PRAK

Protein level used designations for MAPKAP Kinase 5

  • mitogen-activated protein kinase-activated protein kinase 5
  • MAP kinase-activated protein kinase 5
  • MAP kinase-activated protein kinase 5-like
  • MAPK-activated protein kinase 5
  • MAPKAP kinase 5
  • MAPKAPK-5
  • p38-regulated/activated protein kinase
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