MBD4 Produits
(Methyl-CpG Binding Domain Protein 4 (MBD4))
Catégories
The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013].
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Catégories MBD4 en vedette
MBD4 Anticorps
High quality antibodies with extensive validation data.
MBD4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
MBD4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB
Validations
- (3)
- (1)
N° du produit
ABIN1881532
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (1)
- (1)
N° du produit
ABIN537317
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Rat
Application
WB
Validations
- (2)
N° du produit
ABIN3044062
Quantité
100 μg
Fiche technique
Fiche technique
MBD4 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6224403
Quantité
96 tests
Fiche technique
Fiche technique
MBD4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123938
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1310474
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1310473
Quantité
25 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits MBD4
: "Evidence that active demethylation mechanisms maintain the genome of carcinoma in situ cells hypomethylated in the adult testis." dans: British journal of cancer, Vol. 110, Issue 3, pp. 668-78, (2014) (PubMed).: "Polymorphisms in the base excision repair pathway and graft-versus-host disease." dans: Leukemia, Vol. 24, Issue 8, pp. 1470-5, (2010) (PubMed).
: "Association between genetic variants in the base excision repair pathway and outcomes after hematopoietic cell transplantations." dans: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, Vol. 16, Issue 8, pp. 1084-9, (2010) (PubMed).
: "A Large-scale genetic association study of esophageal adenocarcinoma risk." dans: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).
: "Dynamic changes in the localization of five members of the methyl binding domain (MBD) gene family during murine and bovine preimplantation embryo development." dans: Molecular reproduction and development, Vol. 75, Issue 1, pp. 48-59, (2007) (PubMed).
: "Homologous pairing of 15q11-13 imprinted domains in brain is developmentally regulated but deficient in Rett and autism samples." dans: Human molecular genetics, Vol. 14, Issue 6, pp. 785-97, (2005) (PubMed).
Synonymes et noms alternatifs relatifs à MBD4
methyl-CpG binding domain 4, DNA glycosylase (MBD4), methyl-CpG binding domain protein 4 (Mbd4), methyl-CpG binding domain 4 DNA glycosylase (Mbd4), MED1, Med1Protein level used designations for MBD4
- 3,N(4)-ethenocytosine glycosylase
- G/5-fluorouracil mismatch glycosylase with biphasic kinetics
- G/T mismatch glycosylase
- G/U mismatch glycosylase
- methyl-CpG-binding domain protein 4
- methyl-CpG-binding endonuclease 1
- methyl-CpG-binding protein MBD4
- mismatch-specific DNA N-glycosylase
- putative methyl-CpG binding protein
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