MBD1 Produits
(Methyl-CpG Binding Domain Protein 1 (MBD1))
Catégories
The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions\; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides\; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Feb 2011].
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Catégories MBD1 en vedette
MBD1 Anticorps
High quality antibodies with extensive validation data.
MBD1 Kits ELISA
Reliable ELISA kits for a wide range of species.
MBD1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
MBD1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (4)
N° du produit
ABIN517760
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
N° du produit
ABIN517761
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (2)
- (2)
N° du produit
ABIN517757
Quantité
50 μL
Fiche technique
Fiche technique
MBD1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Validations
N° du produit
ABIN1142345
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1142346
Quantité
96 tests
Fiche technique
Fiche technique
MBD1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1310462
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1310463
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7423543
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits MBD1
: "SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage." dans: Cell reports, (2015) (PubMed).: "SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation." dans: Nature communications, Vol. 6, pp. 6569, (2015) (PubMed).
: "Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability." dans: Journal of cell science, Vol. 127, Issue Pt 13, pp. 2910-9, (2014) (PubMed).
: "The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance." dans: Nature immunology, Vol. 15, Issue 3, pp. 258-65, (2014) (PubMed).
: "The centriolar satellite protein Cep131 is important for genome stability." dans: Journal of cell science, Vol. 125, Issue Pt 20, pp. 4770-9, (2012) (PubMed).
: "Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine." dans: Nucleic acids research, Vol. 38, Issue 11, pp. e125, (2010) (PubMed).
: "Epigenetic silence of ankyrin-repeat-containing, SH3-domain-containing, and proline-rich-region- containing protein 1 (ASPP1) and ASPP2 genes promotes tumor growth in hepatitis B virus-positive ..." dans: Hepatology (Baltimore, Md.), Vol. 51, Issue 1, pp. 142-53, (2009) (PubMed).
: "Methods in cancer epigenetics and epidemiology." dans: Methods in molecular biology (Clifton, N.J.), Vol. 471, pp. 273-88, (2008) (PubMed).
: "Dynamic changes in the localization of five members of the methyl binding domain (MBD) gene family during murine and bovine preimplantation embryo development." dans: Molecular reproduction and development, Vol. 75, Issue 1, pp. 48-59, (2007) (PubMed).
: "Role of the polycomb repressive complex 2 in acute promyelocytic leukemia." dans: Cancer cell, Vol. 11, Issue 6, pp. 513-25, (2007) (PubMed).
Synonymes et noms alternatifs relatifs à MBD1
methyl-CpG binding domain protein 1 (MBD1), methyl-CpG binding domain protein 1 (Mbd1), CCDC11, CXXC3, Cxxc3, PCM1, RFTProtein level used designations for MBD1
- CXXC-type zinc finger protein 3
- methyl-CpG binding domain protein 1 isoform PCM1
- methyl-CpG-binding domain protein 1
- protein containing methyl-CpG-binding domain 1
- the regulator of fibroblast growth factor 2 (FGF-2) transcription
- methyl-CpG-binding protein MBD1
- coiled-coil domain containing 11
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