MLH1 Produits
(MutL Homolog 1 (MLH1))
Catégories
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009].
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Catégories MLH1 en vedette
MLH1 Anticorps
High quality antibodies with extensive validation data.
MLH1 Kits ELISA
Reliable ELISA kits for a wide range of species.
MLH1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
MLH1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, FACS, ICC
Validations
- (6)
N° du produit
ABIN7193525
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS
Validations
- (7)
N° du produit
ABIN7193587
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, IHC (p), PLA
Validations
- (7)
N° du produit
ABIN561826
Quantité
100 μg
Fiche technique
Fiche technique
MLH1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6957921
Quantité
96 tests
Fiche technique
Fiche technique
MLH1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124036
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1311006
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1311004
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits MLH1
: "Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid ..." dans: Molecular & cellular proteomics : MCP, Vol. 17, Issue 1, pp. 146-159, (2019) (PubMed).: "miRNA-148b regulates radioresistance in non-small lung cancer cells via regulation of MutL homologue 1." dans: Bioscience reports, Vol. 36, Issue 3, (2016) (PubMed).
: "Modulation of mismatch repair and genomic stability by miR-155. ..." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 15, pp. 6982-7, (2010) (PubMed).
: "Nuclear overexpression of mitotic regulatory proteins in biliary tract cancer: correlation with clinicopathologic features and patient survival." dans: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 2, pp. 417-23, (2009) (PubMed).
: "High-dose rapid and standard induction chemotherapy for patients aged over 1 year with stage 4 neuroblastoma: a randomised trial." dans: The lancet oncology, Vol. 9, Issue 3, pp. 247-56, (2008) (PubMed).
: "Gene-related cancer spectrum in families with hereditary non-polyposis colorectal cancer (HNPCC)." dans: Familial cancer, Vol. 7, Issue 2, pp. 163-72, (2008) (PubMed).
: "CXCR6 is expressed on T cells in both T helper type 1 (Th1) inflammation and allergen-induced Th2 lung inflammation but is only a weak mediator of chemotaxis." dans: Immunology, Vol. 121, Issue 4, pp. 555-64, (2007) (PubMed).
: "A novel role for DNA mismatch repair and the autophagic processing of chemotherapy drugs in human tumor cells." dans: Autophagy, Vol. 3, Issue 4, pp. 368-70, (2007) (PubMed).
: "Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over." dans: Nature genetics, Vol. 13, Issue 3, pp. 336-42, (1996) (PubMed).
: "Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 6, pp. 1950-4, (1995) (PubMed).
Synonymes et noms alternatifs relatifs à MLH1
mutL homolog 1 (MLH1), CG11482 gene product from transcript CG11482-RB (Mlh1), mutL homolog 1 S homeolog (mlh1.S), mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (mlh1), DNA mismatch repair protein Mlh1 (LOC588545), mutL homolog 1 (mlh1), mutL homolog 1 (Mlh1), 1110035C23Rik, AI317206, AI325952, AI561766, CG11482, COCA2, Dmel\\CG11482, dmlh-1, dmlh1, FCC2, hMLH1, HNPCC, HNPCC2, LOC100232198, MLH1, zgc:66301Protein level used designations for MLH1
- MutL protein homolog 1
- CG11482-PA
- CG11482-PB
- Mlh1-PA
- Mlh1-PB
- DNA mismatch repair protein Mlh1
- mutL-like protein 1
- mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- DNA mismatch repair protein Mlh1-like
- colon cancer, nonpolyposis type 2
- mutL protein homolog 1
- mismatch repair protein 1
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