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MKNK1 Produits

(MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Catégories

This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012].

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Catégories MKNK1 en vedette

MKNK1 Anticorps

High quality antibodies with extensive validation data.

MKNK1 Kits ELISA

Reliable ELISA kits for a wide range of species.

MKNK1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MKNK1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (6)
N° du produit ABIN563699
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (4)
N° du produit ABIN522034
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (4)
N° du produit ABIN522031
Quantité 100 μg
Fiche technique Fiche technique

MKNK1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380779
Quantité 2 x 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380848
Quantité 2 x 96 tests
Fiche technique Fiche technique

MKNK1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310976
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1310974
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
N° du produit ABIN5509020
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MKNK1

Girotti, Silva, George, Morilak: "Ciliary neurotrophic factor signaling in the rat orbitofrontal cortex ameliorates stress-induced deficits in reversal learning." dans: Neuropharmacology, Vol. 160, pp. 107791, (2019) (PubMed).

Pan, Hou, Zhang, Zhao, Hua, Wang, He, Jiang, Hu, Zhang: "Inhibitory effect and molecular mechanism of mesenchymal stem cells on NSCLC cells." dans: Molecular and cellular biochemistry, Vol. 441, Issue 1-2, pp. 63-76, (2018) (PubMed).

Cuesta, Xi, Schneider: "Structural basis for competitive inhibition of eIF4G-Mnk1 interaction by the adenovirus 100-kilodalton protein." dans: Journal of virology, Vol. 78, Issue 14, pp. 7707-16, (2004) (PubMed).

Orton, Ling, Waskiewicz, Cooper, Merrick, Korneeva, Rhoads, Sonenberg, Traugh: "Phosphorylation of Mnk1 by caspase-activated Pak2/gamma-PAK inhibits phosphorylation and interaction of eIF4G with Mnk." dans: The Journal of biological chemistry, Vol. 279, Issue 37, pp. 38649-57, (2004) (PubMed).

Ueda, Watanabe-Fukunaga, Fukuyama, Nagata, Fukunaga: "Mnk2 and Mnk1 are essential for constitutive and inducible phosphorylation of eukaryotic initiation factor 4E but not for cell growth or development." dans: Molecular and cellular biology, Vol. 24, Issue 15, pp. 6539-49, (2004) (PubMed).

OLoghlen, González, Piñeiro, Pérez-Morgado, Salinas, Martín: "Identification and molecular characterization of Mnk1b, a splice variant of human MAP kinase-interacting kinase Mnk1." dans: Experimental cell research, Vol. 299, Issue 2, pp. 343-55, (2004) (PubMed).

Knauf, Tschopp, Gram: "Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2." dans: Molecular and cellular biology, Vol. 21, Issue 16, pp. 5500-11, (2001) (PubMed).

Pyronnet: "Phosphorylation of the cap-binding protein eIF4E by the MAPK-activated protein kinase Mnk1." dans: Biochemical pharmacology, Vol. 60, Issue 8, pp. 1237-43, (2000) (PubMed).

Fukunaga, Hunter: "MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates." dans: The EMBO journal, Vol. 16, Issue 8, pp. 1921-33, (1997) (PubMed).

Synonymes et noms alternatifs relatifs à MKNK1

MAP kinase interacting serine/threonine kinase 1 (MKNK1), MAP kinase interacting serine/threonine kinase 1 (mknk1), MAP kinase-interacting serine/threonine kinase 1 (Mknk1), MAP kinase interacting serine/threonine kinase 1 (Mknk1), MAP kinase interacting serine/threonine kinase 1 S homeolog (mknk1.S), 2410048M24Rik, MAPK signal-integrating kinase 1, MKNK1, mknk1, MNK1, Mnk1, mnk1, zgc:171912

Protein level used designations for MKNK1

  • MAP kinase signal-integrating kinase 1
  • MAP kinase-interacting serine/threonine-protein kinase 1
  • MAPK signal-integrating kinase 1
  • MAP kinase interacting serine/threonine kinase 1
  • mnk1
  • MAP kinase-interacting kinase 1
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