Mre11 Produits
(MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
Catégories
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog\; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Catégories Mre11 en vedette
Mre11 Anticorps
High quality antibodies with extensive validation data.
Mre11 Kits ELISA
Reliable ELISA kits for a wide range of species.
Mre11 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Mre11 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (3)
- (4)
N° du produit
ABIN3016250
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Chicken, Hamster, Human, Mouse, Rat
Application
WB, IHC, IF, IP, ICC, ChIP, FACS
Validations
- (5)
N° du produit
ABIN363310
Quantité
0.05 mL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
N° du produit
ABIN7443944
Quantité
100 μL
Fiche technique
Fiche technique
Mre11 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380501
Quantité
2 x 96 tests
Fiche technique
Fiche technique
Mre11 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1311266
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3093919
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3135392
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits Mre11
: "MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining." dans: Molecular cell, Vol. 71, Issue 2, pp. 332-342.e8, (2019) (PubMed).: "Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination." dans: Nature communications, Vol. 9, Issue 1, pp. 3872, (2019) (PubMed).
: "Depletion of the RNA binding protein HNRNPD impairs homologous recombination by inhibiting DNA-end resection and inducing R-loop accumulation." dans: Nucleic acids research, Vol. 47, Issue 8, pp. 4068-4085, (2019) (PubMed).
: "UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors. ..." dans: Cell, Vol. 176, Issue 3, pp. 505-519.e22, (2019) (PubMed).
: "PPARγ Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis." dans: Cell reports, Vol. 26, Issue 5, pp. 1333-1343.e7, (2019) (PubMed).
: "Hypoosmotic stress induces R loop formation in nucleoli and ATR/ATM-dependent silencing of nucleolar transcription." dans: Nucleic acids research, Vol. 47, Issue 13, pp. 6811-6825, (2019) (PubMed).
: "C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex." dans: Molecular cell, (2019) (PubMed).
: "Increased error-free DNA repair gene expression through reprogramming in human iPS cells." dans: Regenerative therapy, Vol. 11, pp. 101-105, (2019) (PubMed).
: "Rat Glioma Cell-Based Functional Characterization of Anti-Stress and Protein Deaggregation Activities in the Marine Carotenoids, Astaxanthin and Fucoxanthin." dans: Marine drugs, Vol. 17, Issue 3, (2019) (PubMed).
: "Nanostructure of Clustered DNA Damage in Leukocytes after In-Solution Irradiation with the Alpha Emitter Ra-223." dans: Cancers, Vol. 11, Issue 12, (2019) (PubMed).
Synonymes et noms alternatifs relatifs à Mre11
MRE11 homolog A, double strand break repair nuclease (mre11a), MRE11 homolog, double strand break repair nuclease (MRE11), MRE11A homolog A, double strand break repair nuclease (Mre11a), MRE11 homolog A, double strand break repair nuclease (Mre11a), ATLD, HNGS1, Mre11, MRE11, Mre11b, MRE11B, wu:faa63d12, zgc:64018Protein level used designations for Mre11
- meiotic recombination 11 homolog A
- MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
- MRE11 homolog 1
- MRE11 homolog A
- double-strand break repair protein MRE11A
- meiotic recombination 11 homolog 1
- mmMRE11A
- AT-like disease
- DNA recombination and repair protein
- endo/exonuclease Mre11
- meiotic recombination 11-like protein
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