NOTCH3 Produits
(Notch 3 (NOTCH3))
Catégories
This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008].
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Catégories NOTCH3 en vedette
NOTCH3 Anticorps
High quality antibodies with extensive validation data.
NOTCH3 Kits ELISA
Reliable ELISA kits for a wide range of species.
NOTCH3 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
NOTCH3 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse, Rat
Application
IHC, IF
Validations
- (7)
N° du produit
ABIN7074862
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, IF, IHC (p)
Validations
- (1)
- (3)
N° du produit
ABIN390159
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (1)
- (3)
N° du produit
ABIN3023484
Quantité
100 μL
Fiche technique
Fiche technique
NOTCH3 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968971
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968972
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958226
Quantité
96 tests
Fiche technique
Fiche technique
NOTCH3 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7275361
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7275366
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7275362
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits NOTCH3
: "Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes." dans: Nature communications, Vol. 10, Issue 1, pp. 2817, (2019) (PubMed).: "Pulmonary pericytes regulate lung morphogenesis." dans: Nature communications, Vol. 9, Issue 1, pp. 2448, (2018) (PubMed).
: "Involvement of Notch2 in all‑trans retinoic acid‑induced inhibition of mouse embryonic palate mesenchymal cell proliferation." dans: Molecular medicine reports, Vol. 16, Issue 3, pp. 2538-2546, (2017) (PubMed).
: "The Expression of Notch 1 and Notch 3 in Gallbladder Cancer and Their Clinicopathological Significance." dans: Pathology oncology research : POR, Vol. 22, Issue 3, pp. 483-92, (2017) (PubMed).
: "The proteins interacting with C-terminal of μ receptor are identified by bacterial two-hybrid system from brain cDNA library in morphine-dependent rats." dans: Life sciences, Vol. 143, pp. 156-67, (2016) (PubMed).
: "Characterization of Notch Signalling Pathway Members in Normal Prostate, Prostatic Intraepithelial Neoplasia (PIN) and Prostatic Adenocarcinoma." dans: Pathology oncology research : POR, Vol. 22, Issue 1, pp. 87-94, (2015) (PubMed).
: "Mouse model of CADASIL reveals novel insights into Notch3 function in adult hippocampal neurogenesis." dans: Neurobiology of disease, Vol. 75, pp. 131-41, (2015) (PubMed).
: "Notch3 is necessary for neuronal differentiation and maturation in the adult spinal cord." dans: Journal of cellular and molecular medicine, Vol. 18, Issue 10, pp. 2103-16, (2014) (PubMed).
: "Reactive oxygen species- and DNA damage response-dependent NK cell activating ligand upregulation occurs at transcriptional levels and requires the transcriptional factor E2F1." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 2, pp. 950-60, (2014) (PubMed).
: "Von Willebrand factor inhibits mature smooth muscle gene expression through impairment of Notch signaling." dans: PLoS ONE, Vol. 8, Issue 9, pp. e75808, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à NOTCH3
notch 3 (NOTCH3), notch 3 (Notch3), notch 3 (notch3), AW229011, CADASIL, CASIL, fa14b08, hpbk, IMF2, N3, notch5, wu:fa14b08Protein level used designations for NOTCH3
- Notch homolog 3
- neurogenic locus notch homolog protein 3
- Notch gene homolog 3
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