NOTCH3 anticorps (C-Term)

N° du produit ABIN390159

Cité dans 1 publication. Cet anticorps anti-NOTCH3 Polyclonal Lapin (Clone RB02199) (ABIN390159) détecte spécifiquement NOTCH3 dans WB, IF et IHC (p). L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour NOTCH3 anticorps (C-Term) (ABIN390159)

Antigène: NOTCH3 (Notch 3 (NOTCH3))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOTCH3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB02199

Détail du produit anti-NOTCH3 anticorps

Épitope: AA 2291-2321, C-Term

Homologie: H

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This NOTCH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2291-2321 amino acids from the C-terminal region of human NOTCH3.

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-NOTCH3 (ABIN390159)

Liu, Yang, Wang, Miao, Liu, Li, Zou, Li, Liang, Zeng, Chen: "The Expression of Notch 1 and Notch 3 in Gallbladder Cancer and Their Clinicopathological Significance." dans: Pathology oncology research : POR, Vol. 22, Issue 3, pp. 483-92, (2017) (PubMed).

Détails sur NOTCH3

Antigène: NOTCH3 (Notch 3 (NOTCH3))

Autre désignation: NOTCH3

Sujet: NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

Poids moléculaire: 243631

ID gène: 4854

NCBI Accession: NP_000426

UniProt: Q9UM47

Pathways: Signalisation Notch