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OGT Produits

(O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:polypeptide-N-Acetylglucosaminyl Transferase) (OGT))
This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2009].

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Catégories OGT en vedette

OGT Anticorps

High quality antibodies with extensive validation data.

OGT Kits ELISA

Reliable ELISA kits for a wide range of species.

OGT Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

OGT recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (8)
N° du produit ABIN3022708
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IHC (p), IP, ICC, FACS
Validations
  • (8)
N° du produit ABIN2856718
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Rat
Application WB, ELISA, IHC, IF, FACS
Validations
  • (6)
N° du produit ABIN190863
Quantité 100 μg
Fiche technique Fiche technique

OGT recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958285
Quantité 96 tests
Fiche technique Fiche technique

OGT recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1313359
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3094291
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3136462
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits OGT

Lucena, Carvalho-Cruz, Donadio, Oliveira, de Queiroz, Marinho-Carvalho, Sola-Penna, de Paula, Gondim, McComb, Costello, Whelan, Todeschini, Dias: "Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation." dans: The Journal of biological chemistry, Vol. 291, Issue 25, pp. 12917-29, (2016) (PubMed).

Banerjee, Sangwan, McGinn, Chugh, Dudeja, Vickers, Saluja: "Triptolide-induced cell death in pancreatic cancer is mediated by O-GlcNAc modification of transcription factor Sp1." dans: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 33927-38, (2013) (PubMed).

Ise, Goto, Komura, Akaike: "Engulfment and clearance of apoptotic cells based on a GlcNAc-binding lectin-like property of surface vimentin." dans: Glycobiology, Vol. 22, Issue 6, pp. 788-805, (2012) (PubMed).

Allison, Wamsley, Kumar, Li, Gray, Hart, Jones, Mayo: "Modification of RelA by O-linked N-acetylglucosamine links glucose metabolism to NF-?B acetylation and transcription." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 42, pp. 16888-93, (2012) (PubMed).

Taylor, Parker, Hazel, Soesanto, Fuller, Yazzie, McClain: "Glucose deprivation stimulates O-GlcNAc modification of proteins through up-regulation of O-linked N-acetylglucosaminyltransferase." dans: The Journal of biological chemistry, Vol. 283, Issue 10, pp. 6050-7, (2008) (PubMed).

Majumdar, Wright, Markowitz, Martinez-Hernandez, Raghow, Solomon: "Insulin stimulates and diabetes inhibits O-linked N-acetylglucosamine transferase and O-glycosylation of Sp1." dans: Diabetes, Vol. 53, Issue 12, pp. 3184-92, (2004) (PubMed).

Synonymes et noms alternatifs relatifs à OGT

O-linked N-acetylglucosamine (GlcNAc) transferase L homeolog (ogt.L), super sex combs (sxc), O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1 (ogt.1), O-linked N-acetylglucosamine (GlcNAc) transferase (OGT), O-linked N-acetylglucosamine (GlcNAc) transferase (ogt), O-linked GlcNAc transferase (GL50803_12081), O-linked GlcNAc transferase (GL50803_41701), o-linked GlcNAc transferase (THAPSDRAFT_264441), O-linked GlcNAc transferase (spyA), O-linked N-acetylglucosamine (GlcNAc) transferase (Ogt), O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) (Ogt), 1110038P24Rik, 4831420N21Rik, AI115525, BcDNA:GH04245, CG10392, Dmel\\CG10392, fm81g08, HRNT1, l(2)02637, l(2)NC130, O-GLCNAC, OGT, Ogt, ogt, Ogtl, P1201, SXC, Sxc, sxc/Ogt, wu:fc12b01, wu:fm81g08

Protein level used designations for OGT

  • O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
  • O-linked GlcNAc transferase
  • UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase
  • CG10392-PA
  • CG10392-PB
  • CG10392-PC
  • O-glycosyltransferase
  • O-linked N-acetylglucosamine transferase
  • lethal (2) NC130
  • sxc-PA
  • sxc-PB
  • sxc-PC
  • O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 1
  • copy I
  • ogta
  • UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
  • o-linked GlcNAc transferase
  • TPR repeat-containing protein
  • UDP-N-acetylglucosamine:peptide N-acetylglucosaminyltransferase
  • O linked N-acetylglucosamine transferase
  • O-GlcNAc transferase subunit p110
  • O-linked N-acetylglucosamine transferase 110 kDa subunit
  • UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase
  • O-GlcNAc transferase p110 subunit
  • uridinediphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyl transferase
  • O linked N-acetylglucosamine transferase like
  • UDP-N-acetylglucosaminyltransferase
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