ORC2 Produits
(Origin Recognition Complex Subunit 2 (ORC2))
Catégories
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate. [provided by RefSeq, Oct 2010].
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Catégories ORC2 en vedette
ORC2 Anticorps
High quality antibodies with extensive validation data.
ORC2 Kits ELISA
Reliable ELISA kits for a wide range of species.
ORC2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ORC2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (1)
- (5)
N° du produit
ABIN562076
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
N° du produit
ABIN2855601
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IP
Validations
- (1)
- (1)
N° du produit
ABIN108579
Quantité
50 μL
Fiche technique
Fiche technique
ORC2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Validations
N° du produit
ABIN1146513
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1146514
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Validations
N° du produit
ABIN1146515
Quantité
96 tests
Fiche technique
Fiche technique
ORC2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1313650
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3094298
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3122769
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits ORC2
: "SLFN11 Blocks Stressed Replication Forks Independently of ATR." dans: Molecular cell, Vol. 69, Issue 3, pp. 371-384.e6, (2019) (PubMed).: "RBM3-regulated genes promote DNA integrity and affect clinical outcome in epithelial ovarian cancer." dans: Translational oncology, Vol. 4, Issue 4, pp. 212-21, (2011) (PubMed).
: "A conserved physical and functional interaction between the cell cycle checkpoint clamp loader and DNA ligase I of eukaryotes." dans: The Journal of biological chemistry, Vol. 282, Issue 31, pp. 22721-30, (2007) (PubMed).
: "Identification of HsORC4, a member of the human origin of replication recognition complex." dans: The Journal of biological chemistry, Vol. 272, Issue 45, pp. 28247-51, (1997) (PubMed).
: "Mouse and human homologues of the yeast origin of replication recognition complex subunit ORC2 and chromosomal localization of the cognate human gene ORC2L." dans: Genomics, Vol. 31, Issue 1, pp. 119-22, (1996) (PubMed).
Synonymes et noms alternatifs relatifs à ORC2
Origin recognition complex subunit 2 (Orc2), origin recognition complex second largest subunit 2 (ORC2), origin recognition complex subunit 2 (ORC2), origin recognition complex, subunit 2 (Orc2), origin recognition complex subunit 2 S homeolog (orc2.S), Origin recognition complex subunit 2 (orc-2), ATORC2, AU041563, CG3041, Dmel\\CG3041, DmORC 2, DmORC2, DmOrc2, DmOrc2p, F13M22.6, F13M22_6, fs(3)293, fs(3)293-19, k43, l(3)88Ab, l(3)A5, l(3)dsl5, l(3)K43, l(3)k43, l(3)SG44, ORC, Orc-2, ORC2, orc2, orc2-a, ORC2L, Orc2l, orc2l, Orc2p, ORIGIN RECOGNITION COMPLEX SECOND LARGEST SUBUNIT 2, origin recognition complex second largest subunit 2, rDmORC, xorc2Protein level used designations for ORC2
- CG3041-PA
- Orc2-PA
- lethal(3)88Ab
- origin recognition complex
- origin recognition complex subunit 2
- origin recognition complex protein 2 homolog
- origin recognition complex, subunit 2 homolog
- origin recognition complex, subunit 2-like
- origin recognition complex subunit 2 homolog
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