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PAX8 Produits

(Paired Box 8 (PAX8))
This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010].

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Catégories PAX8 en vedette

PAX8 Anticorps

High quality antibodies with extensive validation data.

PAX8 Kits ELISA

Reliable ELISA kits for a wide range of species.

PAX8 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PAX8 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF, IHC (p), IP, ICC, ChIP
Validations
  • (2)
  • (8)
N° du produit ABIN2855097
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, FACS
Validations
  • (7)
N° du produit ABIN7193697
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, FACS, IF, StM
Validations
  • (6)
N° du produit ABIN6940924
Quantité 100 μg
Fiche technique Fiche technique

PAX8 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969128
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative DNA-Binding ELISA
Validations
N° du produit ABIN5648503
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6951205
Quantité 96 tests
Fiche technique Fiche technique

PAX8 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN2752880
Quantité 2 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124298
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1314087
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PAX8

Shi, Yin, Cai, Yan, Jia, Ma, Zhang, Zhang, Gu, Zhang, Di, Zhuang: "PAX8 regulon in human ovarian cancer links lineage dependency with epigenetic vulnerability to HDAC inhibitors." dans: eLife, Vol. 8, (2020) (PubMed).

Sun, Lu, Wu, Ouyang, Xing, Hou, Shi, Wu: "PTEN-knockdown disrupts the morphology, growth pattern and function of Nthy-Ori 3-1 cells by downregulating PAX8 expression." dans: Oncology letters, Vol. 18, Issue 6, pp. 6732-6740, (2019) (PubMed).

Kang, Kumar, Liao, Lichti-Kaiser, Gerrish, Liao, Refetoff, Jothi, Jetten: "GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation." dans: The Journal of clinical investigation, (2018) (PubMed).

Adler, Corona, Lee, Rodriguez-Malave, Mhawech-Fauceglia, Sowter, Hazelett, Lawrenson, Gayther: "The PAX8 cistrome in epithelial ovarian cancer." dans: Oncotarget, Vol. 8, Issue 65, pp. 108316-108332, (2018) (PubMed).

di Martino, De Luca, Grassi, Federici, Alfonsi, Signore, Addario, De Salvo, Francescangeli, Sanchez, Tirelli, Muto, Sperduti, Sentinelli, Costantini, Pasquini, Milella, Haoui, Simone, Gallucci et al.: "Renal cancer: new models and approach for personalizing therapy. ..." dans: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 217, (2018) (PubMed).

Ludwig, Alaggio, Zin, Peron, Guzzardo, Benini, Righi, Gambarotti: "BCOR-CCNB3 Undifferentiated Sarcoma-Does Immunohistochemistry Help in the Identification?" dans: Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society, Vol. 20, Issue 4, pp. 321-329, (2017) (PubMed).

Elias, Emori, Westerling, Long, Budina-Kolomets, Li, MacDuffie, Davis, Holman, Lawney, Freedman, Quackenbush, Brown, Drapkin: "Epigenetic remodeling regulates transcriptional changes between ovarian cancer and benign precursors." dans: JCI insight, Vol. 1, Issue 13, (2016) (PubMed).

Imberti, Tomasoni, Ciampi, Pezzotta, Derosas, Xinaris, Rizzo, Papadimou, Novelli, Benigni, Remuzzi, Morigi: "Renal progenitors derived from human iPSCs engraft and restore function in a mouse model of acute kidney injury." dans: Scientific reports, Vol. 5, pp. 8826, (2015) (PubMed).

McKnight, Cohen, Siddiqui: "Utility of paired box gene 8 (PAX8) expression in fluid and fine-needle aspiration cytology: an immunohistochemical study of metastatic ovarian serous carcinoma." dans: Cancer cytopathology, Vol. 118, Issue 5, pp. 298-302, (2010) (PubMed).

Chia, Sharifah, Reena, Zubaidah, Clarence-Ko, Rohaizak, Naqiyah, Srijit, Hisham, Asmiati, Rafie: "Fluorescence in situ hybridization analysis using PAX8- and PPARG-specific probes reveals the presence of PAX8-PPARG translocation and 3p25 aneusomy in follicular thyroid neoplasms." dans: Cancer genetics and cytogenetics, Vol. 196, Issue 1, pp. 7-13, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à PAX8

paired box 8 (PAX8), paired box 8 (pax8), paired box 8 (Pax8), paired box 8 L homeolog (pax8.L), pax-8, PAX-8, Pax-8, PAX8, XPax-8, XPax8

Protein level used designations for PAX8

  • paired box 8
  • paired box gene 8
  • paired box protein Pax-8
  • paired domain gene 8
  • Pax-8 protein
  • Pax-8 DNA-binding transcription factor
  • XPax-8
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