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PBK Produits

(PDZ Binding Kinase (PBK))

Catégories

This genes encodes a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. [provided by RefSeq, Jul 2008].

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Catégories PBK en vedette

PBK Anticorps

High quality antibodies with extensive validation data.

PBK Kits ELISA

Reliable ELISA kits for a wide range of species.

PBK Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PBK recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (2)
  • (7)
N° du produit ABIN969345
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), IF
Validations
  • (7)
N° du produit ABIN527757
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p), FACS
Validations
  • (2)
  • (4)
N° du produit ABIN1881635
Quantité 400 μL
Fiche technique Fiche technique

PBK recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6951206
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380317
Quantité 2 x 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1141112
Quantité 96 tests
Fiche technique Fiche technique

PBK recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
N° du produit ABIN5569604
Quantité 5 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
N° du produit ABIN5569603
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124331
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PBK

Park, Nishidate, Nakamura, Katagiri: "Critical roles of T-LAK cell-originated protein kinase in cytokinesis." dans: Cancer science, Vol. 101, Issue 2, pp. 403-11, (2010) (PubMed).

Mulder, Björling, Jonasson, Wernérus, Hober, Hökfelt, Uhlén: "Tissue profiling of the mammalian central nervous system using human antibody-based proteomics." dans: Molecular & cellular proteomics : MCP, Vol. 8, Issue 7, pp. 1612-22, (2009) (PubMed).

Oh, Zhu, Cho, Lee, Kang, Kim, Zykova, Bode, Dong: "T-lymphokine-activated killer cell-originated protein kinase functions as a positive regulator of c-Jun-NH2-kinase 1 signaling and H-Ras-induced cell transformation." dans: Cancer research, Vol. 67, Issue 11, pp. 5186-94, (2007) (PubMed).

Zykova, Zhu, Lu, Higgins, Tatsumi, Abe, Bode, Dong: "Lymphokine-activated killer T-cell-originated protein kinase phosphorylation of histone H2AX prevents arsenite-induced apoptosis in RPMI7951 melanoma cells." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 12, Issue 23, pp. 6884-93, (2006) (PubMed).

Fujibuchi, Abe, Takeuchi, Ueda, Shigemoto, Yamamoto, Kito: "Expression and phosphorylation of TOPK during spermatogenesis." dans: Development, growth & differentiation, Vol. 47, Issue 9, pp. 637-44, (2005) (PubMed).

Nandi, Tidwell, Karp, Rapoport: "Protein expression of PDZ-binding kinase is up-regulated in hematologic malignancies and strongly down-regulated during terminal differentiation of HL-60 leukemic cells." dans: Blood cells, molecules & diseases, Vol. 32, Issue 1, pp. 240-5, (2004) (PubMed).

Simons-Evelyn, Bailey-Dell, Toretsky, Ross, Fenton, Kalvakolanu, Rapoport: "PBK/TOPK is a novel mitotic kinase which is upregulated in Burkitt's lymphoma and other highly proliferative malignant cells." dans: Blood cells, molecules & diseases, Vol. 27, Issue 5, pp. 825-9, (2002) (PubMed).

Zhao, Dai, Zhao, Xia, Zhou, Wang, Gu, Ying, Xie, Mao: "PDZ-binding kinase participates in spermatogenesis." dans: The international journal of biochemistry & cell biology, Vol. 33, Issue 6, pp. 631-6, (2001) (PubMed).

Abe, Matsumoto, Kito, Ueda: "Cloning and expression of a novel MAPKK-like protein kinase, lymphokine-activated killer T-cell-originated protein kinase, specifically expressed in the testis and activated lymphoid cells." dans: The Journal of biological chemistry, Vol. 275, Issue 28, pp. 21525-31, (2000) (PubMed).

Gaudet, Branton, Lue: "Characterization of PDZ-binding kinase, a mitotic kinase." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 10, pp. 5167-72, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à PBK

PDZ binding kinase (PBK), PDZ binding kinase (pbk), PDZ binding kinase (Pbk), PDZ binding kinase L homeolog (pbk.L), 2810434B10Rik, AW538537, CT84, D14Ertd732e, Nori-3, PBK, SPK, topk, TOPK, zgc:92050

Protein level used designations for PBK

  • PDZ binding kinase
  • T-LAK cell-originated protein kinase
  • MAPKK-like protein kinase
  • cancer/testis antigen 84
  • lymphokine-activated killer T-cell-originated protein kinase
  • serine/threonine protein kinase
  • spermatogenesis-related protein kinase
  • PDZ-binding kinase
  • PBK, PDZ-binding kinase
  • lymphokine-activated killer T-cell-originated protein kinase homolog
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