p107 Produits
(Retinoblastoma-Like 1 (p107) (RBL1))
Catégories
The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories p107 en vedette
p107 Anticorps
High quality antibodies with extensive validation data.
p107 Kits ELISA
Reliable ELISA kits for a wide range of species.
p107 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
p107 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
N° du produit
ABIN389640
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, PLA
Validations
- (3)
N° du produit
ABIN562602
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (3)
- (1)
N° du produit
ABIN1881732
Quantité
400 μL
Fiche technique
Fiche technique
p107 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969920
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1155324
Quantité
96 tests
Fiche technique
Fiche technique
p107 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1317569
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3135610
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3094884
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits p107
: "XPO1 inhibition by selinexor induces potent cytotoxicity against high grade bladder malignancies." dans: Oncotarget, Vol. 9, Issue 77, pp. 34567-34581, (2018) (PubMed).: "p107-Dependent recruitment of SWI/SNF to the alkaline phosphatase promoter during osteoblast differentiation." dans: Bone, Vol. 69, pp. 47-54, (2014) (PubMed).
: "The 140-kD isoform of CD56 (NCAM1) directs the molecular pathogenesis of ischemic cardiomyopathy." dans: The American journal of pathology, Vol. 182, Issue 4, pp. 1205-18, (2013) (PubMed).
: "B55alpha PP2A holoenzymes modulate the phosphorylation status of the retinoblastoma-related protein p107 and its activation." dans: The Journal of biological chemistry, Vol. 285, Issue 39, pp. 29863-73, (2010) (PubMed).
: "A Large-scale genetic association study of esophageal adenocarcinoma risk." dans: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).
: "Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis." dans: British journal of cancer, Vol. 101, Issue 8, pp. 1461-8, (2009) (PubMed).
: "p107 inhibits G1 to S phase progression by down-regulating expression of the F-box protein Skp2." dans: The Journal of cell biology, Vol. 168, Issue 1, pp. 55-66, (2005) (PubMed).
: "The cell cycle-regulated B-Myb transcription factor overcomes cyclin-dependent kinase inhibitory activity of p57(KIP2) by interacting with its cyclin-binding domain." dans: The Journal of biological chemistry, Vol. 278, Issue 45, pp. 44255-64, (2003) (PubMed).
: "Mullerian Inhibiting Substance inhibits cervical cancer cell growth via a pathway involving p130 and p107." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 26, pp. 15601-6, (2003) (PubMed).
: "Relief of YY1 transcriptional repression by adenovirus E1A is mediated by E1A-associated protein p300." dans: Genes & development, Vol. 9, Issue 10, pp. 1188-98, (1995) (PubMed).
Synonymes et noms alternatifs relatifs à p107
retinoblastoma-like 1 L homeolog (rbl1.L), RB transcriptional corepressor like 1 (RBL1), retinoblastoma-like 1 (p107) (rbl1), retinoblastoma-like 1 (rbl1), retinoblastoma-like 1 (p107) (RBL1), RB transcriptional corepressor like 1 (rbl1), retinoblastoma-like 1 (p107) (Rbl1), RB transcriptional corepressor like 1 (Rbl1), AW547426, CP107, fj58e06, p107, prb1, PRB1, wu:fj58e06Protein level used designations for p107
- retinoblastoma-like 1 (p107)
- retinoblastoma-like protein 1
- retinoblastoma-like protein 1-like
- 107 kDa retinoblastoma-associated protein
- cellular protein 107
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