P2RX7 Produits
(Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
Catégories
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010].
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Catégories P2RX7 en vedette
P2RX7 Anticorps
High quality antibodies with extensive validation data.
P2RX7 Kits ELISA
Reliable ELISA kits for a wide range of species.
P2RX7 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
P2RX7 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA, FACS, ICC
Validations
- (6)
N° du produit
ABIN5542663
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human, Rat
Application
WB, IHC (p)
Validations
- (1)
- (3)
N° du produit
ABIN2855803
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (1)
- (2)
N° du produit
ABIN651861
Quantité
400 μL
Fiche technique
Fiche technique
P2RX7 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969783
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958994
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1146777
Quantité
96 tests
Fiche technique
Fiche technique
P2RX7 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN2752876
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3085439
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3085438
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits P2RX7
: "Pannexin 3 activates P2X7 receptor to mediate inflammation and cartilage matrix degradation in temporomandibular joint osteoarthritis." dans: Cell biology international, Vol. 47, Issue 7, pp. 1183-1197, (2023) (PubMed).: "ATP in the tumour microenvironment drives expression of nfP2X7, a key mediator of cancer cell survival." dans: Oncogene, Vol. 38, Issue 2, pp. 194-208, (2019) (PubMed).
: "P2RX7 Deletion in T Cells Promotes Autoimmune Arthritis by Unleashing the Tfh Cell Response." dans: Frontiers in immunology, Vol. 10, pp. 411, (2019) (PubMed).
: "New role of P2X7 receptor in an Alzheimer's disease mouse model." dans: Molecular psychiatry, Vol. 24, Issue 1, pp. 108-125, (2019) (PubMed).
: "TCR-pMHC encounter differentially regulates transcriptomes of tissue-resident CD8 T cells." dans: European journal of immunology, Vol. 48, Issue 1, pp. 128-150, (2018) (PubMed).
: "P2X7 receptor in spinal tuberculosis: Gene polymorphisms and protein levels in Chinese Han population." dans: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, Vol. 57, pp. 138-144, (2017) (PubMed).
: "P2X7 receptor-dependent tuning of gut epithelial responses to infection." dans: Immunology and cell biology, Vol. 95, Issue 2, pp. 178-188, (2016) (PubMed).
: "P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation." dans: International journal of molecular medicine, Vol. 35, Issue 5, pp. 1179-88, (2015) (PubMed).
: "P2X7 Receptor Antagonism Attenuates the Intermittent Hypoxia-induced Spatial Deficits in a Murine Model of Sleep Apnea Via Inhibiting Neuroinflammation and Oxidative Stress." dans: Chinese medical journal, Vol. 128, Issue 16, pp. 2168-75, (2015) (PubMed).
: "Lidocaine preferentially inhibits the function of purinergic P2X7 receptors expressed in Xenopus oocytes." dans: Anesthesia and analgesia, Vol. 120, Issue 3, pp. 597-605, (2015) (PubMed).
Synonymes et noms alternatifs relatifs à P2RX7
purinergic receptor P2X 7 (P2RX7), purinergic receptor P2X, ligand-gated ion channel, 7 (p2rx7), P2X purinoceptor 7 (LOC100458463), purinergic receptor P2X, ligand-gated ion channel, 7 (P2rx7), purinergic receptor P2X 7 (P2rx7), AI467586, P2RX7, P2X(7), P2X7, p2x7, P2X7R, p2xr7Protein level used designations for P2RX7
- P2X purinoceptor 7
- purinergic receptor P2X, ligand-gated ion channel, 7
- p2X purinoceptor 7-like
- ATP receptor
- P2X7 receptor
- P2Z receptor
- purinergic receptor P2X7 variant A
- P2X7 purinoceptor
- purinergic receptor P2X7
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