PDE1B Produits
(phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))
Catégories
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011].
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Catégories PDE1B en vedette
PDE1B Anticorps
High quality antibodies with extensive validation data.
PDE1B Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PDE1B recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS
Validations
- (1)
- (6)
N° du produit
ABIN1724781
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Rat
Application
WB, ELISA, IHC, FACS
Validations
- (1)
- (7)
N° du produit
ABIN1724782
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS
Validations
- (1)
- (5)
N° du produit
ABIN1724783
Quantité
100 μL
Fiche technique
Fiche technique
PDE1B recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1314453
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3085911
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3121336
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits PDE1B
: "Confinement Sensing and Signal Optimization via Piezo1/PKA and Myosin II Pathways." dans: Cell reports, Vol. 15, Issue 7, pp. 1430-41, (2016) (PubMed).: "Phosphodiesterases in the rat ovary: effect of cAMP in primordial follicles." dans: Reproduction (Cambridge, England), Vol. 150, Issue 1, pp. 11-20, (2016) (PubMed).
: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." dans: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).
: "Cyclic GMP catabolism up-regulation in MRL/lpr lupus-prone mice is associated with organ remodeling." dans: Biochimica et biophysica acta, Vol. 1842, Issue 7, pp. 916-26, (2014) (PubMed).
: "Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1." dans: Molecular nutrition & food research, Vol. 55, Issue 11, pp. 1677-89, (2012) (PubMed).
: "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." dans: Cellular signalling, Vol. 23, Issue 1, pp. 152-60, (2011) (PubMed).
: "cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle." dans: American journal of physiology. Endocrinology and metabolism, Vol. 301, Issue 2, pp. E342-50, (2011) (PubMed).
: "Distinct metabolism of cyclic adenosine monophosphate in regulatory and helper CD4+ T cells." dans: Molecular immunology, Vol. 47, Issue 4, pp. 678-84, (2010) (PubMed).
: "Inhibition of PDE3, PDE4 and PDE7 potentiates glucocorticoid-induced apoptosis and overcomes glucocorticoid resistance in CEM T leukemic cells." dans: Biochemical pharmacology, Vol. 79, Issue 3, pp. 321-9, (2009) (PubMed).
: "Chronic haloperidol and clozapine produce different patterns of effects on phosphodiesterase-1B, -4B, and -10A expression in rat striatum." dans: Neuropharmacology, Vol. 54, Issue 4, pp. 745-54, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à PDE1B
phosphodiesterase 1B, Ca2+-calmodulin dependent (Pde1b), phosphodiesterase 1B (PDE1B), phosphodiesterase 1B (Pde1b), 63kDa, Aop2, Pde1b1, PDE1B1, PDES1BProtein level used designations for PDE1B
- 63 kDa Cam-PDE
- calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B
- cam-PDE 1B
- phosphodiesterase 1B, Ca2+-calmodulin dependent, 63 kDa
- phosphodiesterase 1B1, Ca2+-calmodulin dependent, 63 kDa
- calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase
- calmodulin-stimulated phosphodiesterase PDE1B1
- presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B
- anti-oxidant protein 2
- cyclic nucleotide phosphodiesterase (CaM-PDE)
- phosphodiesterase 1B, Ca2+calmodulin dependent
- phosphodiesterase 1B1 Ca2+-calmodulin dependent 63 kDa
- phosphodiesterase IB calmodulin-dependent
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