PDK4 Produits
(Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))
Catégories
This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin. [provided by RefSeq, Jul 2008].
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Catégories PDK4 en vedette
PDK4 Anticorps
High quality antibodies with extensive validation data.
PDK4 Kits ELISA
Reliable ELISA kits for a wide range of species.
PDK4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PDK4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, IF, IHC (p)
Validations
- (24)
- (6)
N° du produit
ABIN391039
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (7)
N° du produit
ABIN7439630
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, mIHC
Validations
- (1)
- (7)
N° du produit
ABIN3028963
Quantité
0.2 mL
Fiche technique
Fiche technique
PDK4 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969802
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6953337
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
N° du produit
ABIN1116875
Quantité
96 tests
Fiche technique
Fiche technique
PDK4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
N° du produit
ABIN5570522
Quantité
5 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124722
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1314556
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PDK4
: "Immune Checkpoint Blockade Improves Chemotherapy in the PyMT Mammary Carcinoma Mouse Model." dans: Frontiers in oncology, Vol. 10, pp. 1771, (2020) (PubMed).: "High hepatic expression of PDK4 improves survival upon multimodal treatment of colorectal liver metastases." dans: British journal of cancer, Vol. 120, Issue 7, pp. 675-688, (2019) (PubMed).
: "Overexpression of lncRNA EPB41L4A-AS1 Induces Metabolic Reprogramming in Trophoblast Cells and Placenta Tissue of Miscarriage." dans: Molecular therapy. Nucleic acids, Vol. 18, pp. 518-532, (2019) (PubMed).
: "Defining the contribution of skeletal muscle pyruvate dehydrogenase alpha 1 (Pdha1) to exercise performance and insulin action." dans: American journal of physiology. Endocrinology and metabolism, (2018) (PubMed).
: "The antineoplastic drug, trastuzumab, dysregulates metabolism in iPSC-derived cardiomyocytes." dans: Clinical and translational medicine, Vol. 6, Issue 1, pp. 5, (2017) (PubMed).
: "On the pivotal role of PPARα in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 30, Issue 8, pp. 2684-97, (2017) (PubMed).
: "Arsenic silences hepatic PDK4 expression through activation of histone H3K9 methylatransferase G9a." dans: Toxicology and applied pharmacology, Vol. 304, pp. 42-7, (2017) (PubMed).
: "Transforming Growth Factor β Mediates Drug Resistance by Regulating the Expression of Pyruvate Dehydrogenase Kinase 4 in Colorectal Cancer." dans: The Journal of biological chemistry, Vol. 291, Issue 33, pp. 17405-16, (2017) (PubMed).
: "The microRNA-182-PDK4 axis regulates lung tumorigenesis by modulating pyruvate dehydrogenase and lipogenesis." dans: Oncogene, Vol. 36, Issue 7, pp. 989-998, (2017) (PubMed).
: "Pyruvate dehydrogenase kinase 4 exhibits a novel role in the activation of mutant KRAS, regulating cell growth in lung and colorectal tumour cells." dans: Oncogene, Vol. 36, Issue 44, pp. 6164-6176, (2017) (PubMed).
Synonymes et noms alternatifs relatifs à PDK4
pyruvate dehydrogenase kinase 4 (pdk4), pyruvate dehydrogenase kinase 4 (PDK4), pyruvate dehydrogenase kinase, isoenzyme 4 (Pdk4), pyruvate dehydrogenase kinase 4 (Pdk4), AV005916Protein level used designations for PDK4
- pyruvate dehydrogenase kinase 4
- pyruvate dehydrogenase kinase, isoenzyme 4
- pyruvate dehydrogenase kinase, isozyme 4
- [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial
- pyruvate dehydrogenase, lipoamide, kinase isozyme 4, mitochondrial
- pyruvate dehydrogenase kinase isozyme 4
- pyruvate dehydrogenate kinase 4
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