PDGFRA Produits
(Platelet Derived Growth Factor Receptor alpha (PDGFRA))
Catégories
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012].
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Catégories PDGFRA en vedette
PDGFRA Anticorps
High quality antibodies with extensive validation data.
PDGFRA Kits ELISA
Reliable ELISA kits for a wide range of species.
PDGFRA Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PDGFRA recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (2)
- (6)
N° du produit
ABIN5611263
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, IHC (p)
Validations
- (1)
- (4)
N° du produit
ABIN392024
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, FACS, ICC
Validations
- (5)
N° du produit
ABIN5542490
Quantité
0.1 mg
Fiche technique
Fiche technique
PDGFRA recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (6)
N° du produit
ABIN6720580
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969416
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969415
Quantité
96 tests
Fiche technique
Fiche technique
PDGFRA recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7275439
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7275438
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7275440
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PDGFRA
: "Extracellular Vesicles Derived from Acidified Metastatic Melanoma Cells Stimulate Growth, Migration, and Stemness of Normal Keratinocytes." dans: , Vol. 10, Issue 3, (2022) (PubMed).: "SLURP-1 Controls Growth and Migration of Lung Adenocarcinoma Cells, Forming a Complex With α7-nAChR and PDGFR/EGFR Heterodimer." dans: Frontiers in cell and developmental biology, Vol. 9, pp. 739391, (2021) (PubMed).
: "A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma." dans: Scientific reports, Vol. 9, Issue 1, pp. 4902, (2019) (PubMed).
: "The expression of Platelet-derived Growth factor receptors (PDGFRs) and their correlation with overall survival of patients with ovarian cancer." dans: Ginekologia polska, Vol. 90, Issue 5, pp. 242-249, (2019) (PubMed).
: "Clinical genomic sequencing of pediatric and adult osteosarcoma reveals distinct molecular subsets with potentially targetable alterations." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, (2019) (PubMed).
: "AAV9 Edits Muscle Stem Cells in Normal and Dystrophic Adult Mice." dans: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 27, Issue 9, pp. 1568-1585, (2019) (PubMed).
: "An RNA Aptamer Targeting the Receptor Tyrosine Kinase PDGFRα Induces Anti-tumor Effects through STAT3 and p53 in Glioblastoma." dans: Molecular therapy. Nucleic acids, Vol. 14, pp. 131-141, (2019) (PubMed).
: "Identification of a multipotent Twist2-expressing cell population in the adult heart." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 36, pp. E8430-E8439, (2018) (PubMed).
: "A derivative of platelet-derived growth factor receptor alpha binds to the trimer of human cytomegalovirus and inhibits entry into fibroblasts and endothelial cells." dans: PLoS pathogens, Vol. 13, Issue 4, pp. e1006273, (2017) (PubMed).
: "Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations." dans: Cell stem cell, Vol. 21, Issue 2, pp. 179-194.e4, (2017) (PubMed).
Synonymes et noms alternatifs relatifs à PDGFRA
platelet derived growth factor receptor alpha (PDGFRA), platelet derived growth factor receptor, alpha polypeptide (Pdgfra), platelet derived growth factor receptor alpha (Pdgfra), platelet-derived growth factor receptor, alpha polypeptide L homeolog (pdgfra.L), platelet-derived growth factor receptor, alpha polypeptide (PDGFRA), AI115593, APDGFR, CD140a, CD140A, PDGFACE, PDGFR, Pdgfr-2, PDGFR-2, PDGFR-A, PDGFR2, RHEPDGFRAProtein level used designations for PDGFRA
- platelet-derived growth factor receptor, alpha polypeptide
- alpha-type platelet-derived growth factor receptor-like
- Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha)
- CD140 antigen-like family member A
- PDGF alpha chain
- PDGF-R-alpha
- PDGFR-alpha
- alpha-type platelet-derived growth factor receptor
- platelet-derived growth factor alpha receptor
- platelet-derived growth factor receptor alpha
- alpha platelet-derived growth factor receptor
- CD140a antigen
- PDGFRA/BCR fusion
- platelet-derived growth factor receptor 2
- rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein
- tyrosine kinase PDGFR
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