RAR-Related Orphan Receptor C (RORC) (N-Term) Peptide
RORC
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN5513533
Aperçu rapide pour RAR-Related Orphan Receptor C (RORC) (N-Term) Peptide (ABIN5513533)
Antigène
RORC
(RAR-Related Orphan Receptor C (RORC))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Séquence
- DSLHAEVQKQ LQQRQQQQQE PVVKTPPAGA QGADTLTYTL GLPDGQLPLG
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-RORG Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RORC (RAR-Related Orphan Receptor C (RORC))
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Sujet
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The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: TOR, RORG, RZRG, IMD42, NR1F3, RZR-GAMMA
Protein Size: 518 -
ID gène
- 6097
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NCBI Accession
- NM_001001523, NP_001001523
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UniProt
- P51449
Antigène
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