Src Homology 2 Domain Containing Adaptor Protein B (SHB) (N-Term) Peptide
Aperçu rapide pour Src Homology 2 Domain Containing Adaptor Protein B (SHB) (N-Term) Peptide (ABIN8112775)
Antigène
Source
Application
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Protein Region
- N-Term
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Fonction
- SHB Peptide - N-terminal region
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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This is a synthetic peptide designed for use in combination with anti-SHB antibody ( ARP58763_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))
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Sujet
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Background Information: SHB is the adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. SHB may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. SHB may also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. SHB may also regulate IRS1 and IRS2 signaling in insulin-producing cells.
Alternative Symbols: RP11-3J10.8, bA3J10.2
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Poids moléculaire
- 55kDa
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ID gène
- 6461
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NCBI Accession
- NP_003019
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UniProt
- Q15464
Antigène
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