Src Homology 2 Domain Containing Adaptor Protein B (SHB) (N-Term) Peptide
SHB
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits SHB
- SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))
- Protein Region
- N-Term
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-SHB antibody (Catalog #: ARP58763_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))
- Synonymes
- SHB Peptide, RP11-3J10.8 Peptide, bA3J10.2 Peptide, RGD1565350 Peptide, BC028832 Peptide, SH2 domain containing adaptor protein B Peptide, src homology 2 domain-containing transforming protein B Peptide, SHB Peptide, Shb Peptide
- Sujet
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SHB is the adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. SHB may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. SHB may also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. SHB may also regulate IRS1 and IRS2 signaling in insulin-producing cells.
Alias Symbols: RP11-3J10.8, bA3J10.2
Protein Interaction Partner: EPS8,FGFR1,PDGFRB,PIK3R1,SRC,src,CRK,EPS8,GRAP2,GRB2,IL2RB,IL2RG,JAK1,JAK3,KDR,LAT,LCP2,PDGFRA,PIK3R1,PLCG1,SLC39A1,SRC,VAV1,ZAP70,CRK,EPS8,FGFR1,GRB2,IL2RB,IL2RG,JAK1,JAK3,KDR,LAT,LCP2,PIK3R1,PLCG1,SRC,VAV1,ZAP70
Protein Size: 509 - Poids moléculaire
- 55 kDa
- ID gène
- 6461
- NCBI Accession
- NM_003028, NP_003019
- UniProt
- Q15464
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